Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: PTN6 (P29350)
Tyrosine-protein phosphatase non-receptor type 6 (EC 3.1.3.48) (Hematopoietic cell protein-tyrosine phosphatase) (Protein-tyrosine phosphatase 1C) (PTP-1C) (Protein-tyrosine phosphatase SHP-1) (SH-PTP1)
Gene: PTPN6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 28675297
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~Y_phosphatase, Y_phosphatase~Y_phosphatase
Common GO terms GO:0004725 - protein tyrosine phosphatase activity
GO:0004726 - non-membrane spanning protein tyrosine phosphatase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006470 - protein dephosphorylation
and 4 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

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Hs

1 595
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Last updated: 15 Jul 2024