HitPredict

Interactor 1: PTPRA (P18052)
Receptor-type tyrosine-protein phosphatase alpha (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (EC 3.1.3.48) (LCA-related phosphatase) (PTPTY-28)
Gene: PTPRA

Interactor 2: PTPR2 (P80560)
Receptor-type tyrosine-protein phosphatase N2 (R-PTP-N2) (EC 3.1.3.-) (EC 3.1.3.48) (PTP IA-2beta) (Phogrin) (Protein tyrosine phosphatase-NP) (PTP-NP) [Cleaved into: IA-2beta71; IA-2beta64; IA-2beta60]
Gene: Ptprn2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12364328
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Y_phosphatase~Y_phosphatase
Common GO terms	GO:0004725 - protein tyrosine phosphatase activity GO:0016311 - dephosphorylation GO:0043235 - receptor complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 829 Mm			1 1001
+	Mm
		574007 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRN_MOUSE (37-1001): 0: 706: 41.78
+	Hs
		1031991 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRN_HUMAN (37-1001): 0: 670: 40.91
+	Hs
		577018 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTN13_HUMAN (121-1001): 1.13e-148: 491: 16.10
+	Mm
		574008 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRD_MOUSE (583-992): 7.53e-104: 359: 27.43
+	Mm
		573997 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRA_MOUSE (726-992): 1.52e-107: 355: 36.19
+	Mm
		56906 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRF_MOUSE (726-992): 6.36e-98: 341: 35.32
+	Mm
		69645 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRS_MOUSE (584-992): 1.14e-97: 341: 27.25
+	Hs
		576980 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRA_HUMAN (586-992): 6.28e-110: 361: 26.47
+	Mm
		574002 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRE_MOUSE (584-992): 9.88e-99: 328: 25.48
+	Hs
		576983 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRE_HUMAN (584-992): 1e-104: 344: 25.59
+	Hs
		616916 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRB_HUMAN (655-994): 2.56e-114: 390: 31.69
+	Mm
		574010 PTPRA_MOUSE (1-829): 0: 1004: 100.00		S4R1M0_MOUSE (705-989): 1.31e-73: 266: 27.30
+	Hs
		616971 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRD_HUMAN (583-992): 9.44e-104: 359: 27.67
+	Hs
		576984 PTPRA_HUMAN (1-829): 0: 973: 89.50		PTPRG_HUMAN (121-997): 1.98e-75: 273: 13.89
+	Mm
		573998 PTPRA_MOUSE (1-829): 0: 1004: 100.00		PTPRM_MOUSE (727-995): 3.97e-63: 236: 30.33
+	Hs
		1031977 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRS_HUMAN (584-992): 6.19e-100: 348: 27.25
+	Hs
		489957 PTPRS_HUMAN (5-827): 0: 889: 36.84		PTPRF_HUMAN (587-992): 6.54e-98: 341: 26.23
+	Mm
		828098 PTPRD_MOUSE (14-827): 0: 890: 37.85		PTPRE_MOUSE (584-992): 9.88e-99: 328: 25.48