HitPredict

Interactor 1: ARF4 (P18085)
ADP-ribosylation factor 4
Gene: ARF4

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 180 Hs			1 839
+	Hs
		601491 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		FGFR2_HUMAN (203-838): 1.97e-168: 510: 24.89
+	Hs
		384230 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		574596 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73
+	Hs
		507840 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		507936 RAB1A_HUMAN (3-180): 6.71e-68: 207: 22.40		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		574595 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		912860 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		411349 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		574653 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		ROR1_HUMAN (509-821): 2.63e-67: 243: 40.50
+	Hs
		435530 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		537716 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		INSRR_HUMAN (513-820): 1.33e-62: 231: 40.84
+	Rn
		102471 G3V6H0_RAT (5-180): 7.12e-67: 204: 22.65		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	Hs
		574774 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	At
		1340848 Q9M1P5_ARATH (1-180): 2.31e-67: 204: 80.00		BRL2_ARATH (6-173): 1.69e-15: 83.3: 16.67