HitPredict

Interactor 1: ARF4 (P18085)
ADP-ribosylation factor 4
Gene: ARF4

Interactor 2: DEN1B (Q6P3S1)
DENN domain-containing protein 1B (Connecdenn 2) (Protein FAM31B)
Gene: DENND1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	33443570
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005085 - guanyl-nucleotide exchange factor activity GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 180 Hs			1 775
+	Hs
		950639 ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00		DEN1B_HUMAN (1-775): 0: 1006: 100.00
+	Hs
		950508 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		DEN1B_HUMAN (1-775): 0: 1006: 100.00
+	Hs
		950665 ARF5_HUMAN (1-180): 4.28e-74: 221: 90.00		DEN1A_HUMAN (1-660): 0: 642: 50.22
+	Hs
		574717 ARF4_HUMAN (1-180): 5.6e-70: 211: 100.00		DEN1A_HUMAN (1-660): 0: 642: 50.22
+	Hs
		950528 ARF1_HUMAN (1-180): 2.16e-67: 204: 80.56		DEN1A_HUMAN (1-660): 0: 642: 50.22
+	Hs
		912955 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		DEN4C_HUMAN (8-527): 8.59e-133: 435: 17.28
+	Hs
		309465 ARF6_HUMAN (5-179): 3.01e-89: 260: 64.00		MTMR5_HUMAN (10-521): 6.2e-115: 385: 18.12