HitPredict

Interactor 1: EGR1 (P18146)
Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)
Gene: EGR1

Interactor 2: P55G (Q92569)
Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase regulatory subunit gamma) (PI3K regulatory subunit gamma) (PtdIns-3-kinase regulatory subunit gamma) (Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma) (PI3-kinase subunit p55-gamma) (PtdIns-3-kinase regulatory subunit p55-gamma) (p55PIK)
Gene: PIK3R3

Species: Homo sapiens

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19374776
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010628 - positive regulation of gene expression GO:0030217 - T cell differentiation
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 461
+	Hs
		337340 EGR1_HUMAN (1-543): 1.51e-146: 434: 100.00		ABL1_HUMAN (3-461): 1.02e-93: 308: 16.12
+	Hs
		575341 EGR1_HUMAN (1-543): 1.51e-146: 434: 100.00		BLK_HUMAN (285-458): 2.65e-18: 89.2: 23.50
+	Hs
		523018 Z658B_HUMAN (53-542): 1.33e-138: 422: 14.04		SRC_HUMAN (323-459): 8.26e-19: 90.8: 24.14
+	Hs
		548633 EGR1_HUMAN (1-543): 1.51e-146: 434: 100.00		VAV_HUMAN (65-170): 4e-12: 70.6: 27.36
+	Hs
		181794 EGR1_HUMAN (1-543): 1.51e-146: 434: 100.00		SOCS1_HUMAN (46-169): 5.58e-13: 69.8: 23.20
+	Mm
		436786 EGR2_MOUSE (80-425): 2.78e-96: 302: 42.53		CISH_MOUSE (30-146): 3.5e-17: 82.9: 25.69
+	Hs
		412264 ZN615_HUMAN (435-542): 5.72e-19: 92.7: 7.53		FYN_HUMAN (326-459): 6.82e-20: 94.2: 26.06
+	Hs
		562668 ZKSC7_HUMAN (463-542): 2.43e-13: 74.8: 11.25		PLCG2_HUMAN (337-452): 6.98e-12: 69.8: 33.33