Protein: PUR1
Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase)

Gene: PUR1, ADE4
Organism: Saccharomyces cerevisiae S288C
Interactions: 35
UniProt ID: P04046

Gene Ontology (top 5):
GO:0004044 - amidophosphoribosyltransferase activity
GO:0005737 - cytoplasm
GO:0006164 - purine nucleotide biosynthetic process
GO:0006189 - 'de novo' IMP biosynthetic process
GO:0009113 - purine nucleobase biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

400047

PUR1
Amidophosphoribosyltransferase

3

10

High-throughput

0.852

High

400066

SSB2
Ribosome-associated molecular chaperone SSB2

3

10

High-throughput

0.611

High

400059

CYS3
Cystathionine gamma-lyase

2

0

High-throughput

0.576

High

400054

HSC82
ATP-dependent molecular chaperone HSC82

2

5

High-throughput

0.571

High

400049

LTE1
Guanine nucleotide exchange factor LTE1

1

3

High-throughput

0.536

High

400076

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.536

High

400048

GPT
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

1

0

High-throughput

0.518

High

400057

PWP2
Periodic tryptophan protein 2

1

1

High-throughput

0.515

High

400063

KOG1
Target of rapamycin complex 1 subunit KOG1

1

2

High-throughput

0.481

High

400050

TBA1
Tubulin alpha-1 chain

1

4

High-throughput

0.479

High

400060

SMY2
Protein SMY2

1

3

High-throughput

0.479

High

400061

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

400067

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

4

High-throughput

0.479

High

400074

HST2
NAD-dependent protein deacetylase HST2

1

4

High-throughput

0.479

High

400055

MYO2
Myosin-2

1

0

Small-scale

0.460

High

400072

YG3A
Uncharacterized protein YGR130C

1

1

High-throughput

0.457

High

400051

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.445

High

400052

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

400073

RBG2
Ribosome-interacting GTPase 2

1

0

High-throughput

0.438

High

400080

RTN2
Reticulon-like protein 2

1

0

High-throughput

0.438

High

400056

SIS1
Protein SIS1

1

6

High-throughput

0.437

High

400058

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

400062

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

400064

RPN10
26S proteasome regulatory subunit RPN10

1

3

High-throughput

0.437

High

400065

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

400077

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

400078

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

400079

DBP10
ATP-dependent RNA helicase DBP10

1

5

High-throughput

0.437

High

400068

JJJ2
J protein JJJ2

1

0

High-throughput

0.426

High

400069

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

400053

RNA1
Ran GTPase-activating protein 1

2

0

High-throughput

0.313

High

400075

ALO
D-arabinono-1,4-lactone oxidase

1

0

High-throughput

0.282

High

400070

SAP4
SIT4-associating protein SAP4

1

0

High-throughput

0.249

Low

400071

MTHR2
Methylenetetrahydrofolate reductase 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025