Interactor 1: VINC (P18206)
Vinculin (Metavinculin) (MV)
Gene: VCL

Interactor 2: CTNA1 (P35221)
Catenin alpha-1 (Alpha E-catenin) (Cadherin-associated protein) (Renal carcinoma antigen NY-REN-13)
Gene: CTNNA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.929

The method score is based on:

Property Details
Experiments 34079125, 9700171, 26496610, 35271311, 23292143
Identification Methods proximity labelling technology, pull down, affinity chromatography technology, comigration in non denaturing gel electrophoresis, molecular sieving, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Vinculin~Vinculin
Common GO terms GO:0005198 - structural molecule activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005912 - adherens junction
and 7 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1134
Hs

1 906
+ Mm
+ Ce
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Ce
+ Ce
+ Ce
+ Gg
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024