HitPredict

Interactor 1: SYDC (P14868)
Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (Cell proliferation-inducing gene 40 protein)
Gene: DARS1

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 501 Hs			1 768
+	Hs
		576764 SYDC_HUMAN (1-501): 0: 617: 100.00		CUL4A_HUMAN (10-768): 0: 801: 38.32
+	Hs
		1113140 SYK_HUMAN (14-495): 2.24e-154: 454: 18.88		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		576762 SYDC_HUMAN (1-501): 0: 617: 100.00		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		1114830 SYK_HUMAN (14-495): 2.24e-154: 454: 18.88		CUL4A_HUMAN (10-768): 0: 801: 38.32
+	Hs
		576812 SYDC_HUMAN (1-501): 0: 617: 100.00		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1112492 SYK_HUMAN (14-495): 2.24e-154: 454: 18.88		CUL1_HUMAN (18-768): 0: 709: 30.57