HitPredict

Interactor 1: SEC63 (P14906)
Protein translocation protein SEC63 (Protein NPL1) (Sec62/63 complex 73 kDa subunit)
Gene: SEC63

Interactor 2: BIP (P16474)
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein homolog) (GRP-78) (Immunoglobulin heavy chain-binding protein homolog) (BiP)
Gene: KAR2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.937

The method score is based on:

Property Details
Experiments 9199165, 8522580, 9843586, 38747383, 20430885
Identification Methods biochemical, affinity chromatography technology, enzymatic study, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DnaJ~HSP70
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0031204 - post-translational protein targeting to membrane, translocation
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 663
Sc

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Service provided by Combinatics, Japan

Last updated: 11Aug2025