HitPredict

Interactor 1: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Interactor 2: RBP2 (P49792)
E3 SUMO-protein ligase RanBP2 (EC 2.3.2.-) (358 kDa nucleoporin) (Nuclear pore complex protein Nup358) (Nucleoporin Nup358) (Ran-binding protein 2) (RanBP2) (p270)
Gene: RANBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0031267 - small GTPase binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 421 Hs			1 3224
+	Hs
		152761 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD8_HUMAN (2355-3064): 2.79e-42: 174: 17.03
+	Hs
		578469 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD5_HUMAN (2355-3076): 9.38e-42: 172: 16.89
+	Hs
		63873 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD3_HUMAN (2313-3076): 6.96e-42: 172: 16.92
+	Hs
		483381 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		RGPD1_HUMAN (1026-1514): 2.56e-27: 125: 21.86