HitPredict

Interactor 1: ATF1 (P18846)
Cyclic AMP-dependent transcription factor ATF-1 (cAMP-dependent transcription factor ATF-1) (Activating transcription factor 1) (Protein TREB36)
Gene: ATF1

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	8663317, 20730097
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	KIX~pKID
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0065003 - protein-containing complex assembly
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 271 Hs			1 2442
+	Hs
		556933 CREB1_HUMAN (12-270): 7.89e-55: 181: 64.89		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		974401 CREM_HUMAN (5-270): 5.22e-50: 169: 50.88		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Mm
		101435 CREB1_MOUSE (12-270): 3.31e-55: 182: 64.89		F8VPR5_MOUSE (1-2442): 0: 1077: 95.67
+	Mm
		799596 CREB1_MOUSE (12-270): 3.31e-55: 182: 64.89		CBP_MOUSE (1-2442): 0: 1060: 95.22
+	Hs
		547833 ATF2_HUMAN (4-264): 1.41e-26: 109: 18.11		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		556851 CREB1_HUMAN (12-270): 7.89e-55: 181: 64.89		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Mm
		70912 CREB1_MOUSE (12-270): 3.31e-55: 182: 64.89		EP300_MOUSE (1-2426): 0: 867: 53.61
+	Hs
		547790 ATF2_HUMAN (4-264): 1.41e-26: 109: 18.11		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Mm
		70890 ATF2_MOUSE (4-264): 2.33e-23: 100: 18.11		EP300_MOUSE (1-2426): 0: 867: 53.61