HitPredict

Interactor 1: ATF6A (P18850)
Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha) (Activating transcription factor 6 alpha) (ATF6-alpha) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha]
Gene: ATF6

Interactor 2: OS9 (Q13438)
Protein OS-9 (Amplified in osteosarcoma 9)
Gene: OS9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0030968 - endoplasmic reticulum unfolded protein response GO:0034976 - response to endoplasmic reticulum stress GO:0036503 - ERAD pathway
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 670 Hs			1 667
+	Hs
		1034523 ATF6B_HUMAN (63-660): 1.86e-115: 363: 32.90		OS9_HUMAN (1-667): 0: 993: 100.00
+	Hs
		216721 CREB3_HUMAN (192-486): 1.28e-36: 142: 16.03		OS9_HUMAN (1-667): 0: 993: 100.00
+	Hs
		579367 ATF6A_HUMAN (1-670): 0: 590: 100.00		ERLEC_HUMAN (29-229): 1.88e-27: 118: 24.41
+	Hs
		1288810 ATF6B_HUMAN (63-660): 1.86e-115: 363: 32.90		ERLEC_HUMAN (29-229): 1.88e-27: 118: 24.41
+	Hs
		216796 CREB3_HUMAN (192-486): 1.28e-36: 142: 16.03		ERLEC_HUMAN (29-229): 1.88e-27: 118: 24.41