Protein: OSH2
Oxysterol-binding protein homolog 2 (Oxysterol-binding protein-related protein 2) (ORP 2) (OSBP-related protein 2)

Gene: OSH2
Organism: Saccharomyces cerevisiae S288C
Interactions: 54
UniProt ID: Q12451

Gene Ontology (top 5):
GO:0005635 - nuclear envelope
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1046655

MYO5
Myosin-5

5

3

Small-scale

0.939

High

645997

DBF2
Cell cycle protein kinase DBF2

2

2

Small-scale

0.778

High

1084934

OSH2
Oxysterol-binding protein homolog 2

2

13

High-throughput

0.743

High

779030

MYO3
Myosin-3

1

4

High-throughput

0.733

High

818217

SCS2
Vesicle-associated membrane protein-associated protein SCS2

4

20

Small-scale

0.700

High

646281

SEC22
Protein transport protein SEC22

1

1

Small-scale

0.691

High

777245

OSH1
Oxysterol-binding protein homolog 1

1

13

High-throughput

0.665

High

646582

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.647

High

656687

KC11
Casein kinase I homolog 1

1

6

High-throughput

0.647

High

656920

KC12
Casein kinase I homolog 2

1

5

High-throughput

0.647

High

1030272

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

2

High-throughput

0.647

High

525634

HSP71
Heat shock protein SSA1

2

13

High-throughput

0.611

High

812788

LAA1
AP-1 accessory protein LAA1

2

1

High-throughput

0.601

High

836126

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.595

High

801967

KSP1
Serine/threonine-protein kinase KSP1

1

7

High-throughput

0.579

High

1084935

SKS1
Serine/threonine-protein kinase SKS1

1

2

High-throughput

0.579

High

668972

ERG6
Sterol 24-C-methyltransferase ERG6

1

2

Small-scale

0.573

High

1084936

SCS22
Vesicle-associated membrane protein-associated protein SCS22

1

20

Small-scale

0.541

High

746477

SSO1
Protein SSO1

1

8

Small-scale

0.536

High

812303

ATC3
Phospholipid-transporting ATPase DRS2

1

1

High-throughput

0.515

High

823260

SEC9
Protein transport protein SEC9

1

1

Small-scale

0.481

High

727423

HS104
Heat shock protein 104

1

3

High-throughput

0.479

High

1044857

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

1053887

IMB1
Importin subunit beta-1

1

1

High-throughput

0.479

High

1084579

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

796647

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

1

High-throughput

0.470

High

1084493

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.470

High

748107

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

393564

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.445

High

481822

HSP73
Heat shock protein SSA3

1

13

High-throughput

0.445

High

528088

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

546848

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.445

High

577249

SEC63
Protein translocation protein SEC63

1

2

High-throughput

0.445

High

676494

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

742739

HSP7F
Heat shock protein homolog SSE1

1

17

High-throughput

0.445

High

779595

LHS1
Heat shock protein 70 homolog LHS1

1

14

High-throughput

0.445

High

804579

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

820189

SSB2
Ribosome-associated molecular chaperone SSB2

1

12

High-throughput

0.445

High

924080

JJJ1
J protein JJJ1

1

7

High-throughput

0.445

High

510924

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.437

High

708603

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

918135

CDH1
APC/C activator protein CDH1

1

3

Small-scale

0.437

High

1084921

LAS17
Proline-rich protein LAS17

1

2

Small-scale

0.437

High

824594

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

816484

HSP7E
Heat shock protein SSC3, mitochondrial

1

5

High-throughput

0.407

High

1040457

UME1
Transcriptional regulatory protein UME1

1

0

High-throughput

0.282

High

419916

H2A2
Histone H2A.2

1

0

High-throughput

0.269

Low

917957

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

399894

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.249

Low

779383

CENPA
Histone H3-like centromeric protein CSE4

1

0

High-throughput

0.249

Low

1045074

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.249

Low

924527

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low

1046763

PFD5
Prefoldin subunit 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025