HitPredict

Interactor 1: ATF6A (P18850)
Cyclic AMP-dependent transcription factor ATF-6 alpha (cAMP-dependent transcription factor ATF-6 alpha) (Activating transcription factor 6 alpha) (ATF6-alpha) [Cleaved into: Processed cyclic AMP-dependent transcription factor ATF-6 alpha]
Gene: ATF6

Interactor 2: STK40 (Q8N2I9)
Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase) (Sugen kinase 495) (SgK495)
Gene: STK40

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25609649, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 670 Hs			1 435
+	Hs
		579370 ATF6A_HUMAN (1-670): 0: 590: 100.00		TRIB1_HUMAN (155-325): 4.48e-30: 121: 39.31
+	At
		1105390 AI5L5_ARATH (159-379): 4.88e-32: 130: 20.34		KIN10_ARATH (21-427): 8.81e-122: 365: 20.63
+	At
		1105324 BZP16_ARATH (73-374): 5.9e-30: 124: 16.45		KIN10_ARATH (21-427): 8.81e-122: 365: 20.63
+	At
		1105396 ABI5_ARATH (194-382): 1.24e-28: 121: 23.32		KIN10_ARATH (21-427): 8.81e-122: 365: 20.63
+	Hs
		681869 NF2L2_HUMAN (38-370): 2.14e-30: 128: 14.45		AKT1_HUMAN (6-401): 2.8e-119: 358: 21.14
+	At
		1105922 ABI5_ARATH (194-382): 1.24e-28: 121: 23.32		CDPKB_ARATH (10-426): 1.24e-119: 359: 18.29
+	At
		955252 ABI5_ARATH (194-382): 1.24e-28: 121: 23.32		KIN11_ARATH (34-430): 1.98e-119: 359: 21.59
+	At
		1105331 BZP68_ARATH (78-372): 8.35e-27: 114: 16.01		KIN10_ARATH (21-427): 8.81e-122: 365: 20.63
+	At
		187524 ABI5_ARATH (194-382): 1.24e-28: 121: 23.32		CIPKB_ARATH (16-397): 3.6e-120: 358: 19.27
+	At
		1105918 AI5L7_ARATH (215-376): 8.02e-27: 115: 24.54		CDPKB_ARATH (10-426): 1.24e-119: 359: 18.29
+	At
		1105919 AI5L6_ARATH (225-372): 8.55e-27: 115: 24.26		CDPKB_ARATH (10-426): 1.24e-119: 359: 18.29
+	At
		1114761 AI5L7_ARATH (215-376): 8.02e-27: 115: 24.54		CDPKC_ARATH (23-426): 1.38e-119: 359: 19.12
+	At
		955248 AI5L6_ARATH (225-372): 8.55e-27: 115: 24.26		KIN11_ARATH (34-430): 1.98e-119: 359: 21.59
+	Hs
		556790 CREB1_HUMAN (95-357): 2.11e-27: 115: 17.12		AKT1_HUMAN (6-401): 2.8e-119: 358: 21.14
+	At
		1104945 AI5L7_ARATH (215-376): 8.02e-27: 115: 24.54		CDPK4_ARATH (12-426): 8.8e-119: 357: 18.38
+	At
		1105920 AI5L4_ARATH (223-378): 9.7e-19: 90.9: 26.54		CDPKB_ARATH (10-426): 1.24e-119: 359: 18.29
+	At
		1114762 AI5L4_ARATH (223-378): 9.7e-19: 90.9: 26.54		CDPKC_ARATH (23-426): 1.38e-119: 359: 19.12
+	At
		1104946 AI5L4_ARATH (223-378): 9.7e-19: 90.9: 26.54		CDPK4_ARATH (12-426): 8.8e-119: 357: 18.38
+	Mm
		987634 ATF4_MOUSE (76-378): 1.55e-32: 131: 13.25		TRIB3_MOUSE (161-325): 4.57e-26: 110: 38.10
+	Hs
		579283 ATF4_HUMAN (77-378): 2.5e-33: 133: 13.46		TRIB3_HUMAN (161-325): 4.49e-25: 107: 38.10