HitPredict

Interactor 1: GNAZ (P19086)
Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha)
Gene: GNAZ

Interactor 2: EPHA4 (P54764)
Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK)
Gene: EPHA4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 355 Hs			1 986
+	Hs
		444699 GNAI3_HUMAN (1-354): 5.24e-174: 489: 67.23		EPHA4_HUMAN (1-986): 0: 1293: 100.00
+	Hs
		580464 GNAT2_HUMAN (1-354): 3.65e-167: 471: 57.06		EPHA4_HUMAN (1-986): 0: 1293: 100.00
+	Hs
		872647 GNA13_HUMAN (2-354): 1.24e-156: 446: 39.17		EPHA4_HUMAN (1-986): 0: 1293: 100.00
+	Hs
		444674 GNAI3_HUMAN (1-354): 5.24e-174: 489: 67.23		UFO_HUMAN (268-928): 5.13e-150: 469: 23.72
+	Rn
		444646 GNAI3_RAT (1-354): 1.9e-172: 485: 66.95		INSR_RAT (284-952): 7.97e-144: 465: 24.14
+	Hs
		435603 GNAI1_HUMAN (1-354): 9.58e-177: 495: 67.23		IGF1R_HUMAN (394-884): 1.97e-137: 447: 29.47