HitPredict

Interactor 1: ML12A (P19105)
Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)
Gene: MYL12A

Interactor 2: CRCM (P23508)
Colorectal mutant cancer protein (Protein MCC)
Gene: MCC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 171 Hs			1 829
+	Hs
		580614 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		MYH9_HUMAN (135-829): 1.05e-29: 129: 11.75
+	Hs
		159549 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MYH9_HUMAN (135-829): 1.05e-29: 129: 11.75
+	Hs
		580616 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		MYH11_HUMAN (9-718): 1.21e-28: 126: 12.59
+	Hs
		624341 MYL9_HUMAN (14-171): 2.29e-64: 196: 94.30		MYH9_HUMAN (135-829): 1.05e-29: 129: 11.75
+	Hs
		159551 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MYH11_HUMAN (9-718): 1.21e-28: 126: 12.59
+	Hs
		580615 ML12A_HUMAN (1-171): 2.06e-65: 199: 100.00		MYH10_HUMAN (130-825): 5.43e-24: 111: 10.96
+	Hs
		159550 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MYH10_HUMAN (130-825): 5.43e-24: 111: 10.96
+	Dm
		773034 SQH_DROME (1-171): 2.38e-60: 186: 80.46		MYSN_DROME (137-829): 8.69e-28: 123: 11.26
+	Hs
		159635 ML12B_HUMAN (13-171): 4.64e-65: 198: 99.37		MYH15_HUMAN (1-695): 1.17e-23: 109: 9.73
+	Hs
		624342 MYL9_HUMAN (14-171): 2.29e-64: 196: 94.30		MYH10_HUMAN (130-825): 5.43e-24: 111: 10.96
+	Mm
		1143166 Q6ZWQ9_MOUSE (1-171): 4.56e-64: 196: 97.09		MYH10_MOUSE (130-825): 2.76e-23: 108: 10.82
+	Hs
		501101 MLRV_HUMAN (9-165): 2.99e-55: 173: 58.23		MYH1_HUMAN (10-654): 7.16e-25: 114: 11.23
+	Dm
		404219 MLR_DROME (8-162): 4.11e-30: 110: 41.14		MYSA_DROME (235-829): 6.95e-22: 104: 10.87
+	Ce
		361122 MLR1_CAEEL (23-169): 2.25e-39: 133: 49.32		MYO1_CAEEL (425-828): 2.26e-13: 76.7: 10.84
+	Ce
		361123 MLR2_CAEEL (23-169): 1.93e-39: 133: 49.32		MYO1_CAEEL (425-828): 2.26e-13: 76.7: 10.84
+	Ce
		361111 MLR1_CAEEL (23-169): 2.25e-39: 133: 49.32		MYO4_CAEEL (494-825): 1.9e-10: 67.1: 10.53
+	Ce
		361112 MLR2_CAEEL (23-169): 1.93e-39: 133: 49.32		MYO4_CAEEL (494-825): 1.9e-10: 67.1: 10.53
+	Hs
		648467 CALL3_HUMAN (31-92): 1.25e-10: 58.2: 27.27		MYH9_HUMAN (135-829): 1.05e-29: 129: 11.75