Protein: AMPN
Aminopeptidase N (AP-N) (hAPN) (EC 3.4.11.2) (Alanyl aminopeptidase) (Aminopeptidase M) (AP-M) (Microsomal aminopeptidase) (Myeloid plasma membrane glycoprotein CD13) (gp150) (CD antigen CD13)

Gene: AMPN, ANPEP
Organism: Homo sapiens
Interactions: 168
UniProt ID: P15144

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001618 - virus receptor activity
GO:0002003 - angiotensin maturation
GO:0004177 - aminopeptidase activity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

580593

AMPN
Aminopeptidase N

2

7

Small-scale

0.759

High

580719

LCAP
Leucyl-cystinyl aminopeptidase

1

7

High-throughput

0.618

High

534586

BIP
Endoplasmic reticulum chaperone BiP

2

4

High-throughput

0.601

High

580610

CD81
CD81 antigen

2

2

Small-scale

0.552

High

580688

TX101
Testis-expressed protein 101

1

1

High-throughput

0.536

High

359913

NB5R3
NADH-cytochrome b5 reductase 3

1

2

High-throughput

0.515

High

409243

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

3

High-throughput

0.515

High

580601

BASI
Basigin

1

2

High-throughput

0.515

High

580616

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

2

High-throughput

0.515

High

580625

PTK7
Inactive tyrosine-protein kinase 7

1

4

High-throughput

0.515

High

580633

S39AE
Metal cation symporter ZIP14

1

2

High-throughput

0.515

High

580721

HYOU1
Hypoxia up-regulated protein 1

1

3

High-throughput

0.515

High

299926

CBPD
Carboxypeptidase D

1

0

High-throughput

0.493

High

580626

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

0

High-throughput

0.493

High

217780

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

220853

XPOT
Exportin-T

1

2

High-throughput

0.479

High

271871

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.479

High

321171

ERLN2
Erlin-2

1

4

High-throughput

0.479

High

323152

TRI37
E3 ubiquitin-protein ligase TRIM37

1

4

High-throughput

0.479

High

336062

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

4

High-throughput

0.479

High

390442

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.479

High

468983

SRPRA
Signal recognition particle receptor subunit alpha

1

1

High-throughput

0.479

High

520733

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

3

High-throughput

0.479

High

548401

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.479

High

557061

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.479

High

573307

ENPL
Endoplasmin

1

5

High-throughput

0.479

High

580596

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

2

High-throughput

0.479

High

580597

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

1

High-throughput

0.479

High

580603

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.479

High

580604

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.479

High

580607

LMAN1
Protein ERGIC-53

1

2

High-throughput

0.479

High

580609

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

580614

BORG5
Cdc42 effector protein 1

1

1

High-throughput

0.479

High

580615

MSHR
Melanocyte-stimulating hormone receptor

1

3

High-throughput

0.479

High

580618

ATP7A
Copper-transporting ATPase 1

1

2

High-throughput

0.479

High

580624

DNJC3
DnaJ homolog subfamily C member 3

1

8

High-throughput

0.479

High

580627

ROCK1
Rho-associated protein kinase 1

1

1

High-throughput

0.479

High

580630

DIP2A
Disco-interacting protein 2 homolog A

1

1

High-throughput

0.479

High

580632

CUL7
Cullin-7

1

1

High-throughput

0.479

High

580635

TRIPB
Thyroid receptor-interacting protein 11

1

1

High-throughput

0.479

High

580639

OCLN
Occludin

1

1

High-throughput

0.479

High

580642

RGPA2
Ral GTPase-activating protein subunit alpha-2

1

1

High-throughput

0.479

High

580648

RGPA1
Ral GTPase-activating protein subunit alpha-1

1

1

High-throughput

0.479

High

580649

SKI3
Superkiller complex protein 3

1

3

High-throughput

0.479

High

580654

KTN1
Kinectin

1

1

High-throughput

0.479

High

580659

LRC57
Leucine-rich repeat-containing protein 57

1

1

High-throughput

0.479

High

580662

NBEA
Neurobeachin

1

1

High-throughput

0.479

High

580666

IPO4
Importin-4

1

3

High-throughput

0.479

High

580667

SYNE2
Nesprin-2

1

2

High-throughput

0.479

High

580669

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

2

High-throughput

0.479

High

580673

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.479

High

580678

FNBP1
Formin-binding protein 1

1

1

High-throughput

0.479

High

580695

TAOK3
Serine/threonine-protein kinase TAO3

1

2

High-throughput

0.479

High

580696

BORG4
Cdc42 effector protein 4

1

1

High-throughput

0.479

High

580698

PPIP2
Proline-serine-threonine phosphatase-interacting protein 2

1

1

High-throughput

0.479

High

580699

WDR41
WD repeat-containing protein 41

1

2

High-throughput

0.479

High

580704

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

1

High-throughput

0.479

High

580713

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.479

High

580714

RRBP1
Ribosome-binding protein 1

1

1

High-throughput

0.479

High

580715

HDAC6
Protein deacetylase HDAC6

1

2

High-throughput

0.479

High

580716

DJB11
DnaJ homolog subfamily B member 11

1

3

High-throughput

0.479

High

580717

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

580718

SEPT9
Septin-9

1

1

Small-scale

0.479

High

580645

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.470

High

123979

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.458

High

129979

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.458

High

160990

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

0

High-throughput

0.458

High

215494

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.458

High

224607

ACTN4
Alpha-actinin-4

1

0

High-throughput

0.458

High

280112

SC22B
Vesicle-trafficking protein SEC22b

1

0

High-throughput

0.458

High

339416

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.458

High

467348

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.458

High

533578

CLUS
Clusterin

1

0

High-throughput

0.458

High

571114

CD99
CD99 antigen

1

0

High-throughput

0.458

High

580594

SL9A1
Sodium/hydrogen exchanger 1

1

0

High-throughput

0.458

High

580598

AKAP5
A-kinase anchor protein 5

1

0

High-throughput

0.458

High

580599

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

Small-scale

0.458

High

580605

NAMPT
Nicotinamide phosphoribosyltransferase

1

0

High-throughput

0.458

High

580608

CLCN7
H(+)/Cl(-) exchange transporter 7

1

0

High-throughput

0.458

High

580612

NPC2
NPC intracellular cholesterol transporter 2

1

0

High-throughput

0.458

High

580613

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.458

High

580617

AKA12
A-kinase anchor protein 12

1

0

High-throughput

0.458

High

580619

COEA1
Collagen alpha-1(XIV) chain

1

0

High-throughput

0.458

High

580621

DYH14
Dynein axonemal heavy chain 14

1

0

High-throughput

0.458

High

580622

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.458

High

580628

ITPR3
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

1

0

High-throughput

0.458

High

580629

DSC3
Desmocollin-3

1

0

High-throughput

0.458

High

580631

GOGB1
Golgin subfamily B member 1

1

0

High-throughput

0.458

High

580637

AAAT
Neutral amino acid transporter B(0)

1

0

High-throughput

0.458

High

580638

VAS1
V-type proton ATPase subunit S1

1

0

High-throughput

0.458

High

580644

ANO6
Anoctamin-6

1

0

High-throughput

0.458

High

580646

UBR4
E3 ubiquitin-protein ligase UBR4

1

0

High-throughput

0.458

High

580650

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

0

High-throughput

0.458

High

580652

VP35L
VPS35 endosomal protein-sorting factor-like

1

0

Small-scale

0.458

High

580653

LYRIC
Protein LYRIC

1

0

High-throughput

0.458

High

580656

AHNK2
Protein AHNAK2

1

0

High-throughput

0.458

High

580660

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

580661

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

0

High-throughput

0.458

High

580663

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.458

High

580664

PCD19
Protocadherin-19

1

0

High-throughput

0.458

High

580668

KCNB2
Potassium voltage-gated channel subfamily B member 2

1

0

High-throughput

0.458

High

580671

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.458

High

580672

EXOC4
Exocyst complex component 4

1

0

High-throughput

0.458

High

580674

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.458

High

580675

S38A2
Sodium-coupled neutral amino acid symporter 2

1

0

High-throughput

0.458

High

580676

TRPM7
Transient receptor potential cation channel subfamily M member 7

1

0

High-throughput

0.458

High

580677

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

580679

RANB9
Ran-binding protein 9

1

0

High-throughput

0.458

High

580682

S29A1
Equilibrative nucleoside transporter 1

1

0

High-throughput

0.458

High

580684

AIF1L
Allograft inflammatory factor 1-like

1

0

High-throughput

0.458

High

580686

RFIP5
Rab11 family-interacting protein 5

1

0

High-throughput

0.458

High

580687

TMM59
Transmembrane protein 59

1

0

High-throughput

0.458

High

580689

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.458

High

580691

NIBA1
Protein Niban 1

1

0

High-throughput

0.458

High

580692

ZY11B
Protein zyg-11 homolog B

1

0

High-throughput

0.458

High

580693

SIK2
Serine/threonine-protein kinase SIK2

1

0

Small-scale

0.458

High

580697

GORS2
Golgi reassembly-stacking protein 2

1

0

High-throughput

0.458

High

580700

VEZA
Vezatin

1

0

High-throughput

0.458

High

580701

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.458

High

580706

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

1

0

High-throughput

0.458

High

580707

RTN4
Reticulon-4

1

0

High-throughput

0.458

High

580710

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

580722

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.458

High

349619

TSN12
Tetraspanin-12

1

3

Small-scale

0.445

High

580600

1433S
14-3-3 protein sigma

1

1

Small-scale

0.445

High

580657

CD177
CD177 antigen

1

1

Small-scale

0.445

High

215702

COCH
Cochlin

1

1

High-throughput

0.437

High

229643

CALU
Calumenin

1

1

High-throughput

0.437

High

371069

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.437

High

417245

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

417928

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.437

High

580602

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.437

High

580606

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

2

High-throughput

0.437

High

580611

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

High-throughput

0.437

High

580620

GOGA3
Golgin subfamily A member 3

1

1

High-throughput

0.437

High

580623

STX5
Syntaxin-5

1

3

High-throughput

0.437

High

580634

RCN1
Reticulocalbin-1

1

1

High-throughput

0.437

High

580636

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

1

High-throughput

0.437

High

580641

INF2
Inverted formin-2

1

2

High-throughput

0.437

High

580643

AR13B
ADP-ribosylation factor-like protein 13B

1

5

High-throughput

0.437

High

580658

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.437

High

580683

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.437

High

580694

DDX47
Probable ATP-dependent RNA helicase DDX47

1

4

High-throughput

0.437

High

580702

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.437

High

580703

SEC12
Guanine nucleotide-exchange factor SEC12

1

1

High-throughput

0.437

High

580720

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

2

High-throughput

0.437

High

580647

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.407

High

580665

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.269

Low

50796

CA226
Uncharacterized protein C1orf226

1

0

High-throughput

0.249

Low

71283

F1712
Protein FAM171A2

1

0

High-throughput

0.249

Low

162083

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.249

Low

226932

LIAS
Lipoyl synthase, mitochondrial

1

0

High-throughput

0.249

Low

566910

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.249

Low

580595

MSH3
DNA mismatch repair protein Msh3

1

0

High-throughput

0.249

Low

580640

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

580651

MPRIP
Myosin phosphatase Rho-interacting protein

1

0

High-throughput

0.249

Low

580655

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.249

Low

580670

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.249

Low

580680

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.249

Low

580681

CDCA3
Cell division cycle-associated protein 3

1

0

High-throughput

0.249

Low

580685

CNPY3
Protein canopy homolog 3

1

0

High-throughput

0.249

Low

580690

OSBL8
Oxysterol-binding protein-related protein 8

1

0

High-throughput

0.249

Low

580705

TM9S3
Transmembrane 9 superfamily member 3

1

0

High-throughput

0.249

Low

580708

OSTC
Oligosaccharyltransferase complex subunit OSTC

1

0

High-throughput

0.249

Low

580709

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.249

Low

580711

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.249

Low

580712

HACD3
Very-long-chain

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025