HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26641092, 27049334
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 475
+	Mm
		449421 NUCL_MOUSE (1-650): 6.1e-99: 321: 76.07		ELAV1_MOUSE (149-471): 9.51e-73: 234: 14.58
+	Hs
		582290 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		516364 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00
+	Hs
		641756 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		U2AF2_HUMAN (1-475): 3.12e-94: 294: 100.00
+	Hs
		582544 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50
+	Hs
		1020306 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		516355 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35
+	Hs
		1055876 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		ELAV3_HUMAN (127-472): 9.26e-67: 220: 13.98
+	Hs
		516484 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		ELAV2_HUMAN (116-470): 6.19e-71: 230: 13.42
+	Hs
		1119141 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PAP1L_HUMAN (142-474): 1.36e-58: 205: 14.07
+	Hs
		516518 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Mm
		665745 PABP1_MOUSE (222-482): 5.43e-43: 167: 15.55		TIA1_MOUSE (253-475): 4.2e-36: 139: 15.70
+	Hs
		516471 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		TIAR_HUMAN (251-473): 6.95e-33: 130: 14.67
+	Hs
		516635 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35
+	Hs
		516730 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50
+	Hs
		516495 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78
+	Hs
		516339 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35
+	Hs
		516689 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP3_HUMAN (41-247): 1.1e-18: 91.1: 14.80