HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: TTP (P26651)
mRNA decay activator protein ZFP36 (G0/G1 switch regulatory protein 24) (Growth factor-inducible nuclear protein NUP475) (Tristetraprolin) (Zinc finger protein 36) (Zfp-36)
Gene: ZFP36

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20221403
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0071364 - cellular response to epidermal growth factor stimulus GO:1990904 - ribonucleoprotein complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 326
+	Hs
		582130 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		TISD_HUMAN (12-223): 1.19e-31: 125: 33.02
+	Hs
		516366 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		TTP_HUMAN (1-326): 7.74e-64: 206: 100.00
+	Hs
		516405 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		TISD_HUMAN (12-223): 1.19e-31: 125: 33.02
+	Hs
		516683 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		UNK_HUMAN (71-300): 1.41e-30: 123: 16.12
+	Hs
		1031452 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		UNK_HUMAN (71-300): 1.41e-30: 123: 16.12