Protein: SDHA
Succinate dehydrogenase flavoprotein subunit (EC 1.3.5.1)

Gene: SDHA
Organism: Escherichia coli K-12
Interactions: 90
UniProt ID: P0AC41

Gene Ontology (top 5):
GO:0000104 - succinate dehydrogenase activity
GO:0005886 - plasma membrane
GO:0006099 - tricarboxylic acid cycle
GO:0008177 - succinate dehydrogenase (quinone) activity
GO:0009055 - electron transfer activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

450117

SDHB
Succinate dehydrogenase iron-sulfur subunit

3

7

Small-scale

0.850

High

498845

COPA
Copper-exporting P-type ATPase

2

1

High-throughput

0.611

High

498819

SDHE
FAD assembly factor SdhE

1

0

High-throughput

0.584

High

498820

FIXC
Protein FixC

1

0

High-throughput

0.578

High

494931

TIG
Trigger factor

2

0

Small-scale

0.576

High

495895

RPOB
DNA-directed RNA polymerase subunit beta

1

1

High-throughput

0.536

High

498817

CAIA
Crotonobetainyl-CoA reductase

1

1

High-throughput

0.536

High

498818

CLPB
Chaperone protein ClpB

1

5

High-throughput

0.536

High

421037

FUMC
Fumarate hydratase class II

1

0

High-throughput

0.513

High

432387

MCP3
Methyl-accepting chemotaxis protein III

1

0

High-throughput

0.513

High

439008

DLD
Quinone-dependent D-lactate dehydrogenase

1

0

High-throughput

0.513

High

491835

KEFF
Glutathione-regulated potassium-efflux system ancillary protein KefF

1

0

High-throughput

0.513

High

492096

PPK1
Polyphosphate kinase

1

0

High-throughput

0.513

High

494811

SUCC
Succinate--CoA ligase [ADP-forming] subunit beta

1

0

High-throughput

0.513

High

495754

YCJF
UPF0283 membrane protein YcjF

1

0

High-throughput

0.513

High

495809

RPOC
DNA-directed RNA polymerase subunit beta'

1

0

High-throughput

0.513

High

498788

GCL
Glyoxylate carboligase

1

0

High-throughput

0.513

High

498790

SUCD
Succinate--CoA ligase [ADP-forming] subunit alpha

1

0

High-throughput

0.513

High

498791

SYY
Tyrosine--tRNA ligase

1

0

High-throughput

0.513

High

498794

ACEK
Isocitrate dehydrogenase kinase/phosphatase

1

0

High-throughput

0.513

High

498796

CIRA
Colicin I receptor

1

0

High-throughput

0.513

High

498801

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

1

0

High-throughput

0.513

High

498805

NARQ
Nitrate/nitrite sensor protein NarQ

1

0

High-throughput

0.513

High

498811

MQO
Malate:quinone oxidoreductase

1

0

High-throughput

0.513

High

498833

ARNA
Bifunctional polymyxin resistance protein ArnA

1

0

High-throughput

0.513

High

498835

YPHE
Uncharacterized ABC transporter ATP-binding protein YphE

1

0

High-throughput

0.513

High

498842

YDGA
Protein YdgA

1

0

High-throughput

0.513

High

498784

DCUS
Sensor histidine kinase DcuS

1

0

High-throughput

0.493

High

498804

FLIF
Flagellar M-ring protein

1

0

High-throughput

0.493

High

490305

CLPX
ATP-dependent Clp protease ATP-binding subunit ClpX

1

2

High-throughput

0.489

High

498785

MIAB
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase

1

1

High-throughput

0.489

High

498786

RIMO
Ribosomal protein uS12 methylthiotransferase RimO

1

1

High-throughput

0.489

High

498802

HEMH
Ferrochelatase

1

1

High-throughput

0.489

High

498806

CAID
Carnitinyl-CoA dehydratase

1

2

High-throughput

0.489

High

498812

RTCR
Transcriptional regulatory protein RtcR

1

3

High-throughput

0.489

High

498814

COBC
Adenosylcobalamin/alpha-ribazole phosphatase

1

2

High-throughput

0.489

High

498822

HYFR
DNA-binding transcriptional activator HyfR

1

3

High-throughput

0.489

High

498831

HSCC
Chaperone protein HscC

1

3

High-throughput

0.489

High

498839

YCJW
Uncharacterized HTH-type transcriptional regulator YcjW

1

1

High-throughput

0.489

High

498843

UACR
Putative uric acid sigma-54-dependent transcriptional regulator UacR

1

3

High-throughput

0.489

High

498834

PAAG
1,2-epoxyphenylacetyl-CoA isomerase

1

2

High-throughput

0.470

High

498803

YIDC
Membrane protein insertase YidC

1

0

Small-scale

0.458

High

497569

THIO
Thioredoxin 1

1

5

Small-scale

0.407

High

420141

KDSB
3-deoxy-manno-octulosonate cytidylyltransferase

1

0

High-throughput

0.279

Low

449837

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

0

High-throughput

0.279

Low

491541

KDSA
2-dehydro-3-deoxyphosphooctonate aldolase

1

0

High-throughput

0.279

Low

492327

RECR
Recombination protein RecR

1

0

High-throughput

0.279

Low

493726

RS2
Small ribosomal subunit protein uS2

1

0

High-throughput

0.279

Low

496190

ATDA
Spermidine N(1)-acetyltransferase

1

0

High-throughput

0.279

Low

496697

PANE
2-dehydropantoate 2-reductase

1

0

High-throughput

0.279

Low

497948

YAJD
Putative HNH nuclease YajD

1

0

High-throughput

0.279

Low

497966

YBAK
Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK

1

0

High-throughput

0.279

Low

498024

YBEL
Uncharacterized protein YbeL

1

0

High-throughput

0.279

Low

498503

DYR
Dihydrofolate reductase

1

0

High-throughput

0.279

Low

498780

DBHB
DNA-binding protein HU-beta

1

0

High-throughput

0.279

Low

498781

ALLR
HTH-type transcriptional repressor AllR

1

0

High-throughput

0.279

Low

498782

ALLS
HTH-type transcriptional activator AllS

1

0

High-throughput

0.279

Low

498783

CAIF
Transcriptional activatory protein CaiF

1

0

High-throughput

0.279

Low

498787

FKBX
FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.279

Low

498792

LPXB
Lipid-A-disaccharide synthase

1

0

High-throughput

0.279

Low

498793

RNH2
Ribonuclease HII

1

0

High-throughput

0.279

Low

498795

SYR
Arginine--tRNA ligase

1

0

High-throughput

0.279

Low

498797

CYSI
Sulfite reductase [NADPH] hemoprotein beta-component

1

0

High-throughput

0.279

Low

498798

YFAA
Uncharacterized protein YfaA

1

0

High-throughput

0.279

Low

498807

CAIB
L-carnitine CoA-transferase

1

0

High-throughput

0.279

Low

498808

GRE1
Probable dehydratase PflD

1

0

High-throughput

0.279

Low

498809

RECT
Protein RecT

1

0

High-throughput

0.279

Low

498810

YBBC
Uncharacterized protein YbbC

1

0

High-throughput

0.279

Low

498813

USPG
Universal stress protein UP12

1

0

High-throughput

0.279

Low

498815

ABPA
Anti-bacteriophage protein A

1

0

High-throughput

0.279

Low

498816

MNGB
Mannosylglycerate hydrolase

1

0

High-throughput

0.279

Low

498821

LCFA
Long-chain-fatty-acid--CoA ligase

1

0

High-throughput

0.279

Low

498823

GGAP
Glucosylglycerate phosphorylase

1

0

High-throughput

0.279

Low

498824

RLHA
23S rRNA 5-hydroxycytidine C2501 synthase

1

0

High-throughput

0.279

Low

498825

YFAQ
Uncharacterized protein YfaQ

1

0

High-throughput

0.279

Low

498826

LYSAC
Peptidyl-lysine N-acetyltransferase PatZ

1

0

High-throughput

0.279

Low

498827

GLXR
2-hydroxy-3-oxopropionate reductase

1

0

High-throughput

0.279

Low

498828

YDFI
Uncharacterized oxidoreductase YdfI

1

0

High-throughput

0.279

Low

498829

YBAP
Uncharacterized protein YbaP

1

0

High-throughput

0.279

Low

498830

YBDR
Uncharacterized zinc-type alcohol dehydrogenase-like protein YbdR

1

0

High-throughput

0.279

Low

498832

PDER
Cyclic di-GMP phosphodiesterase PdeR

1

0

High-throughput

0.279

Low

498836

STFQ
Prophage side tail fiber protein homolog StfQ

1

0

High-throughput

0.279

Low

498837

YDAV
Uncharacterized protein YdaV

1

0

High-throughput

0.279

Low

498838

YDHW
Uncharacterized protein YdhW

1

0

High-throughput

0.279

Low

498840

FADM
Long-chain acyl-CoA thioesterase FadM

1

0

High-throughput

0.279

Low

498841

ALLA
Ureidoglycolate lyase

1

0

High-throughput

0.279

Low

498844

FEAR
Transcriptional activator FeaR

1

0

High-throughput

0.279

Low

498789

NARJ
Nitrate reductase molybdenum cofactor assembly chaperone NarJ

1

0

High-throughput

0.269

Low

498799

NADE
NH(3)-dependent NAD(+) synthetase

1

0

High-throughput

0.269

Low

498800

DPO2
DNA polymerase II

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025