HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	27460707
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 526
+	Hs
		582561 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46
+	Hs
		582580 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35
+	Hs
		516355 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Hs
		516620 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10
+	Hs
		1031411 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10
+	Hs
		516383 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Hs
		726795 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		FUS_HUMAN (1-526): 1.99e-39: 152: 100.00
+	Hs
		642763 ELAV4_HUMAN (464-709): 5.73e-44: 164: 18.82		EWS_HUMAN (3-451): 5.13e-31: 129: 31.05
+	Hs
		516744 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46
+	Hs
		516768 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35
+	Hs
		1031507 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35
+	Sc
		376562 PABP_YEAST (181-555): 3.61e-53: 194: 17.47		PABP_YEAST (263-381): 1.57e-10: 65.5: 18.49
+	Hs
		1119141 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PAP1L_HUMAN (182-382): 2.39e-13: 74.7: 13.43
+	Hs
		516635 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Hs
		516495 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00
+	Hs
		516339 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP1_HUMAN (184-382): 3.08e-12: 71.2: 12.44
+	Hs
		516689 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP3_HUMAN (275-379): 5.23e-10: 63.9: 19.05
+	Zm
		8143 A0A1D6ELH4_MAIZE (204-491): 4.85e-38: 152: 15.53		A0A1D6ELH4_MAIZE (273-381): 6.88e-10: 63.5: 23.85