HitPredict

Interactor 1: VATB1 (P15313)
V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1)
Gene: ATP6V1B1

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (EC 3.6.1.-) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 535
+	Hs
		583103 VATB1_HUMAN (1-513): 0: 650: 100.00		TCPH_HUMAN (4-532): 0: 591: 34.08
+	Hs
		583067 VATB1_HUMAN (1-513): 0: 650: 100.00		TCPG_HUMAN (3-532): 0: 561: 28.33
+	Mm
		1010007 VATB1_MOUSE (1-513): 0: 646: 93.76		TCPG_MOUSE (3-532): 0: 563: 28.52
+	Hs
		583053 VATB1_HUMAN (1-513): 0: 650: 100.00		TCPA_HUMAN (5-533): 0: 541: 34.30
+	Hs
		583066 VATB1_HUMAN (1-513): 0: 650: 100.00		TCPE_HUMAN (1-528): 0: 541: 32.29
+	Dm
		726532 VATB_DROME (21-502): 0: 597: 86.54		Q9W392_DROME (4-535): 0: 568: 70.73
+	Dm
		726436 VATB_DROME (21-502): 0: 597: 86.54		Q9VHL2_DROME (5-525): 0: 554: 31.75
+	Sc
		592257 VATB_YEAST (17-498): 0: 582: 76.97		TCPB_YEAST (9-532): 0: 566: 65.71
+	Sc
		592326 VATB_YEAST (17-498): 0: 582: 76.97		TCPH_YEAST (1-532): 0: 559: 33.09
+	Sc
		592258 VATB_YEAST (17-498): 0: 582: 76.97		TCPG_YEAST (5-528): 0: 537: 28.33
+	Mm
		550732 VATB1_MOUSE (1-513): 0: 646: 93.76		TCPA_MOUSE (7-532): 6.96e-84: 272: 34.67