HitPredict

Interactor 1: RPAB1 (P19388)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4)
Gene: POLR2E

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.739

Property	Details
Experiments	26496610, 9201987, 35271311, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 210 Hs			1 172
+	Hs
		583849 RPAB1_HUMAN (1-210): 1.63e-101: 293: 100.00		RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72
+	Sp
		145818 RPAB1_SCHPO (3-208): 6.38e-83: 246: 43.81		RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42
+	Sc
		593131 RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66		RPB7_YEAST (1-171): 4.45e-63: 193: 42.78
+	Sc
		593134 RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66		RPC8_YEAST (1-158): 1.07e-49: 160: 19.39