HitPredict

Interactor 1: ELK1 (P19419)
ETS domain-containing protein Elk-1
Gene: ELK1

Interactor 2: TFAM (Q00059)
Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)
Gene: TFAM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000976 - transcription cis-regulatory region binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 246
+	Hs
		794532 ETV4_HUMAN (4-144): 2.79e-40: 151: 42.96		TFAM_HUMAN (1-246): 1.85e-62: 197: 100.00
+	Hs
		785352 ELK3_HUMAN (1-427): 1.26e-32: 129: 35.34		TFAM_HUMAN (1-246): 1.85e-62: 197: 100.00
+	Hs
		727934 CHD7_HUMAN (89-419): 1.2e-42: 162: 14.33		SOX6_HUMAN (49-160): 2.17e-25: 106: 12.82
+	Hs
		727814 CHD7_HUMAN (89-419): 1.2e-42: 162: 14.33		SOX5_HUMAN (49-150): 1.14e-23: 101: 12.75
+	Hs
		1311936 CHD7_HUMAN (89-419): 1.2e-42: 162: 14.33		SOX7_HUMAN (121-230): 1.71e-22: 96.4: 14.91
+	Hs
		1332326 CHD7_HUMAN (89-419): 1.2e-42: 162: 14.33		SOX17_HUMAN (119-233): 5.13e-22: 95.6: 14.29
+	Hs
		507380 ERG_HUMAN (5-171): 7.48e-40: 150: 37.06		SOX6_HUMAN (49-160): 2.17e-25: 106: 12.82
+	Hs
		507513 ERG_HUMAN (5-171): 7.48e-40: 150: 37.06		HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61
+	Dm
		115536 ETS3_DROME (5-191): 4.87e-32: 129: 35.29		M9PFG6_DROME (123-232): 2.76e-23: 99.1: 14.91
+	Hs
		727789 FEV_HUMAN (5-189): 6.18e-32: 123: 36.02		SOX5_HUMAN (49-150): 1.14e-23: 101: 12.75
+	Hs
		1304706 FEV_HUMAN (5-189): 6.18e-32: 123: 36.02		HM20A_HUMAN (45-146): 3.64e-24: 100: 19.61
+	Hs
		225727 FLI1_HUMAN (5-168): 8.63e-32: 127: 34.76		SOX15_HUMAN (115-231): 7.87e-21: 89.4: 15.70
+	Hs
		449519 ETS1_HUMAN (5-98): 2.37e-37: 142: 56.38		HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69
+	Hs
		1304724 FEV_HUMAN (5-189): 6.18e-32: 123: 36.02		SOX13_HUMAN (142-226): 5.28e-17: 81.7: 14.61
+	Hs
		175788 FEV_HUMAN (5-189): 6.18e-32: 123: 36.02		HMGB3_HUMAN (46-136): 1.77e-17: 79.8: 21.98
+	Hs
		449582 ETV3_HUMAN (5-418): 3.53e-28: 118: 19.24		HMGB1_HUMAN (27-128): 2.21e-14: 71.7: 15.69