Interactor 1: TNNI3 (P19429)
Troponin I, cardiac muscle (Cardiac troponin I)
Gene: TNNI3

Interactor 2: TNNC1 (P63316)
Troponin C, slow skeletal and cardiac muscles (TN-C)
Gene: TNNC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 18986304, 15134451, 15049709, 29997244, 33961781, 12939162, 12060657, 12122471, 7957210
Identification Methods pull down, fluorescent resonance energy transfer, affinity chromatography technology, x-ray crystallography, unspecified method, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Troponin, EF-hand_8~Troponin
Common GO terms GO:0003009 - skeletal muscle contraction
GO:0005829 - cytosol
GO:0005861 - troponin complex
GO:0031014 - troponin T binding
GO:0048306 - calcium-dependent protein binding
and 4 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 210
Hs

1 161
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Oc
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024