Protein: YTDC1
YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B)

Gene: YTDC1, YTHDC1
Organism: Homo sapiens
Interactions: 181
UniProt ID: Q96MU7

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0001701 - in utero embryonic development
GO:0003723 - RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

833951

CLK2
Dual specificity protein kinase CLK2

5

6

High-throughput

0.725

High

904087

HNRPK
Heterogeneous nuclear ribonucleoprotein K

4

11

High-throughput

0.705

High

1139254

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

4

7

High-throughput

0.700

High

1040391

TRA2A
Transformer-2 protein homolog alpha

4

10

High-throughput

0.695

High

942881

SRPK2
SRSF protein kinase 2

3

9

High-throughput

0.690

High

267537

KHDR3
KH domain-containing, RNA-binding, signal transduction-associated protein 3

3

7

High-throughput

0.675

High

1073379

RBY1F
RNA-binding motif protein, Y chromosome, family 1 member F/J

3

11

High-throughput

0.675

High

1298131

SDCB2
Syntenin-2

4

0

High-throughput

0.668

High

442407

RU17
U1 small nuclear ribonucleoprotein 70 kDa

3

17

High-throughput

0.667

High

745267

RBMX
RNA-binding motif protein, X chromosome

3

13

High-throughput

0.667

High

1197541

RALYL
RNA-binding Raly-like protein

3

14

High-throughput

0.667

High

1250988

SNIP1
Smad nuclear-interacting protein 1

4

0

High-throughput

0.664

High

925106

TRA2B
Transformer-2 protein homolog beta

3

15

High-throughput

0.654

High

608613

H1T
Histone H1t

2

4

High-throughput

0.628

High

834104

CLK3
Dual specificity protein kinase CLK3

2

6

High-throughput

0.628

High

1020312

ELAV2
ELAV-like protein 2

2

14

High-throughput

0.628

High

1201605

ZCH18
Zinc finger CCCH domain-containing protein 18

2

2

High-throughput

0.628

High

1222968

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

2

1

High-throughput

0.628

High

1298130

NXF2
Nuclear RNA export factor 2

2

1

High-throughput

0.628

High

1298148

FBW1B
F-box/WD repeat-containing protein 11

2

7

High-throughput

0.628

High

991851

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

2

7

Small-scale

0.614

High

1019602

ILF2
Interleukin enhancer-binding factor 2

2

1

High-throughput

0.611

High

167001

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

2

6

High-throughput

0.606

High

483449

RBY1A
RNA-binding motif protein, Y chromosome, family 1 member A1

2

11

High-throughput

0.606

High

1070600

RNPS1
RNA-binding protein with serine-rich domain 1

2

11

High-throughput

0.606

High

1298125

SRPK1
SRSF protein kinase 1

1

9

High-throughput

0.602

High

814654

CDX1
Homeobox protein CDX-1

2

0

High-throughput

0.602

High

228399

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

244805

BRD4
Bromodomain-containing protein 4

2

2

High-throughput

0.584

High

1152519

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

2

3

High-throughput

0.584

High

1298138

ANLN
Anillin

2

2

High-throughput

0.584

High

1134184

PHF19
PHD finger protein 19

2

0

High-throughput

0.580

High

1298140

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

370231

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

839056

EMD
Emerin

1

0

Small-scale

0.549

High

47847

RBM47
RNA-binding protein 47

1

14

High-throughput

0.536

High

71207

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

7

High-throughput

0.536

High

201704

MSI1H
RNA-binding protein Musashi homolog 1

1

10

High-throughput

0.536

High

241353

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

7

High-throughput

0.536

High

256323

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

1

High-throughput

0.536

High

321171

PTBP3
Polypyrimidine tract-binding protein 3

1

7

High-throughput

0.536

High

432866

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

10

High-throughput

0.536

High

446748

SNRPA
U1 small nuclear ribonucleoprotein A

1

18

High-throughput

0.536

High

616471

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.536

High

757721

IF4A3
Eukaryotic initiation factor 4A-III

1

8

High-throughput

0.536

High

916319

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.536

High

945324

PRR3
Proline-rich protein 3

1

1

High-throughput

0.536

High

951707

RL19
Large ribosomal subunit protein eL19

1

3

High-throughput

0.536

High

952086

SRSF3
Serine/arginine-rich splicing factor 3

1

12

High-throughput

0.536

High

962291

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

5

High-throughput

0.536

High

964232

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.536

High

984113

SRS11
Serine/arginine-rich splicing factor 11

1

2

High-throughput

0.536

High

993803

SRSF4
Serine/arginine-rich splicing factor 4

1

11

High-throughput

0.536

High

996834

SSRP1
FACT complex subunit SSRP1

1

5

High-throughput

0.536

High

1029043

SRSF6
Serine/arginine-rich splicing factor 6

1

11

High-throughput

0.536

High

1046136

DX39B
Spliceosome RNA helicase DDX39B

1

7

High-throughput

0.536

High

1073834

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

1

16

High-throughput

0.536

High

1084375

SRSF7
Serine/arginine-rich splicing factor 7

1

10

High-throughput

0.536

High

1084576

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

9

High-throughput

0.536

High

1092882

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

4

High-throughput

0.536

High

1116465

LARP7
La-related protein 7

1

19

High-throughput

0.536

High

1268147

LAR4B
La-related protein 4B

1

9

High-throughput

0.536

High

1288616

PABP5
Polyadenylate-binding protein 5

1

8

High-throughput

0.536

High

1298136

LN28A
Protein lin-28 homolog A

1

5

High-throughput

0.536

High

1298139

DDX21
Nucleolar RNA helicase 2

1

5

High-throughput

0.536

High

1298141

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

6

High-throughput

0.536

High

1298147

PURG
Purine-rich element-binding protein gamma

1

2

High-throughput

0.536

High

1298149

RALY
RNA-binding protein Raly

1

5

High-throughput

0.536

High

1298150

ZN346
Zinc finger protein 346

1

1

High-throughput

0.536

High

1298154

YBOX2
Y-box-binding protein 2

1

5

High-throughput

0.536

High

718115

BMI1
Polycomb complex protein BMI-1

1

5

High-throughput

0.515

High

999651

AHNK
Neuroblast differentiation-associated protein AHNAK

1

6

High-throughput

0.515

High

1296817

NSD1
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

1

High-throughput

0.515

High

127846

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.513

High

181239

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

256565

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.513

High

448782

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

508664

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

539109

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

739241

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

911936

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

1298133

PININ
Pinin

1

0

High-throughput

0.513

High

833798

CLK1
Dual specificity protein kinase CLK1

1

6

High-throughput

0.501

High

572570

SPI1
Transcription factor PU.1

1

0

High-throughput

0.493

High

1113904

TBRG1
Transforming growth factor beta regulator 1

1

0

High-throughput

0.493

High

1281818

FBX32
F-box only protein 32

1

0

High-throughput

0.493

High

1298132

S12A5
Solute carrier family 12 member 5

1

0

High-throughput

0.493

High

1298144

UXT
Protein UXT

1

0

High-throughput

0.493

High

1298151

PAI2B
Polyadenylate-binding protein-interacting protein 2B

1

1

High-throughput

0.489

High

257282

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

1

High-throughput

0.481

High

341395

PLMN
Plasminogen

1

3

High-throughput

0.481

High

678300

COR1A
Coronin-1A

1

3

High-throughput

0.481

High

1158995

EDC4
Enhancer of mRNA-decapping protein 4

1

1

High-throughput

0.481

High

1298126

LZTS2
Leucine zipper putative tumor suppressor 2

1

6

High-throughput

0.481

High

1298152

SOX13
Transcription factor SOX-13

1

6

High-throughput

0.481

High

122946

MEN1
Menin

1

2

High-throughput

0.479

High

210211

PRC1
Protein regulator of cytokinesis 1

1

1

High-throughput

0.479

High

298728

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

337532

ABL1
Tyrosine-protein kinase ABL1

1

2

Small-scale

0.479

High

347617

MYC
Myc proto-oncogene protein

1

8

High-throughput

0.479

High

379740

MYCN
N-myc proto-oncogene protein

1

8

High-throughput

0.479

High

387321

P53
Cellular tumor antigen p53

1

4

High-throughput

0.479

High

398066

ISG15
Ubiquitin-like protein ISG15

1

3

High-throughput

0.479

High

453547

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

6

High-throughput

0.479

High

455766

PARP1
Poly [ADP-ribose] polymerase 1

1

8

High-throughput

0.479

High

523111

SRC
Proto-oncogene tyrosine-protein kinase Src

1

4

Small-scale

0.479

High

553468

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

569971

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

651992

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

721192

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

917765

H4
Histone H4

1

3

High-throughput

0.479

High

922317

RL31
Large ribosomal subunit protein eL31

1

3

High-throughput

0.479

High

1037871

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

10

High-throughput

0.479

High

1060876

IMB1
Importin subunit beta-1

1

1

High-throughput

0.479

High

1064046

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.479

High

1066544

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1080248

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1085884

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

1136237

RC3H1
Roquin-1

1

9

High-throughput

0.479

High

1153900

IFIX
Pyrin and HIN domain-containing protein 1

1

3

High-throughput

0.479

High

1188730

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.479

High

1191709

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

5

High-throughput

0.479

High

1235606

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.479

High

1244439

NUP43
Nucleoporin Nup43

1

7

High-throughput

0.479

High

1245134

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1256340

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

1260870

DCAF4
DDB1- and CUL4-associated factor 4

1

4

High-throughput

0.479

High

1269390

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

1288245

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

7

High-throughput

0.479

High

1298127

DDX23
Probable ATP-dependent RNA helicase DDX23

1

3

High-throughput

0.479

High

1298128

ACE2
Angiotensin-converting enzyme 2

1

3

High-throughput

0.479

High

1298129

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

12

High-throughput

0.479

High

1298135

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

1298137

RC3H2
Roquin-2

1

13

High-throughput

0.479

High

1298145

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1298153

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

1

High-throughput

0.479

High

1298134

ATS10
A disintegrin and metalloproteinase with thrombospondin motifs 10

1

1

High-throughput

0.470

High

408901

K1C18
Keratin, type I cytoskeletal 18

1

0

High-throughput

0.460

High

652962

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

750428

COIL
Coilin

1

0

High-throughput

0.458

High

824289

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

899544

MGN
Protein mago nashi homolog

1

0

High-throughput

0.458

High

900808

RHOA
Transforming protein RhoA

1

0

High-throughput

0.458

High

931801

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

941324

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

1062430

PAF15
PCNA-associated factor

1

0

Small-scale

0.458

High

1063562

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1081366

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1220260

DHX40
Probable ATP-dependent RNA helicase DHX40

1

0

High-throughput

0.458

High

1290867

TRI11
E3 ubiquitin-protein ligase TRIM11

1

0

Small-scale

0.458

High

1298155

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

70187

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

3

High-throughput

0.445

High

1044059

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.445

High

1057592

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

3

High-throughput

0.445

High

1284310

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

3

High-throughput

0.445

High

1167403

MPRIP
Myosin phosphatase Rho-interacting protein

1

2

High-throughput

0.439

High

255996

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.437

High

1146744

A16L1
Autophagy-related protein 16-1

1

6

High-throughput

0.437

High

1171291

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

1219437

LMTK2
Serine/threonine-protein kinase LMTK2

1

7

High-throughput

0.437

High

1232687

FBXW8
F-box/WD repeat-containing protein 8

1

8

High-throughput

0.437

High

1255660

RBCC1
RB1-inducible coiled-coil protein 1

1

3

High-throughput

0.437

High

1290030

RNF31
E3 ubiquitin-protein ligase RNF31

1

3

High-throughput

0.437

High

1298143

SLAI2
SLAIN motif-containing protein 2

1

1

High-throughput

0.437

High

56709

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.426

High

1047214

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1124598

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.426

High

1298124

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.426

High

1273611

DVL3
Segment polarity protein dishevelled homolog DVL-3

3

0

High-throughput

0.352

High

1172871

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

889194

KR106
Keratin-associated protein 10-6

2

0

High-throughput

0.316

High

365023

FRIL
Ferritin light chain

1

0

High-throughput

0.279

Low

1231406

CT197
Putative uncharacterized protein encoded by LINC02910

1

0

High-throughput

0.279

Low

327203

TXD12
Thioredoxin domain-containing protein 12

1

0

High-throughput

0.269

Low

206411

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.251

Low

441772

CFAH
Complement factor H

1

0

High-throughput

0.251

Low

995147

GOGA2
Golgin subfamily A member 2

1

0

High-throughput

0.251

Low

1203378

PRSR2
Proline and serine-rich protein 2

1

0

High-throughput

0.251

Low

1298142

SEP10
Septin-10

1

0

High-throughput

0.251

Low

1298146

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.251

Low

1298156

LAMC3
Laminin subunit gamma-3

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024