Protein: Q9W227
Peptidyl-prolyl cis-trans isomerase (PPIase) (EC 5.2.1.8)

Gene: Q9W227, DmelCG2852
Organism: Drosophila melanogaster
Interactions: 236
UniProt ID: Q9W227

Gene Ontology (top 5):
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

871732

FKB12
Peptidyl-prolyl cis-trans isomerase Fkbp12

2

11

High-throughput

0.737

High

1464392

Q9V3V2
peptidylprolyl isomerase

2

9

High-throughput

0.737

High

1474808

Q9VGK3
peptidylprolyl isomerase

2

11

High-throughput

0.737

High

1472535

Q9VEB1
Malate dehydrogenase, mitochondrial

3

5

High-throughput

0.624

High

1263946

Q7K049
AT10229p

2

6

High-throughput

0.594

High

561864

MODU
DNA-binding protein modulo

1

6

High-throughput

0.575

High

668148

PPIA
Peptidyl-prolyl cis-trans isomerase

1

10

High-throughput

0.575

High

1475841

Q9VH81
protein-serine/threonine phosphatase

1

1

High-throughput

0.575

High

1480531

FKB59
FK506-binding protein 59

1

4

High-throughput

0.575

High

195172

O16043
Anon1A4

2

1

High-throughput

0.571

High

357643

INO1
Inositol-3-phosphate synthase

2

1

High-throughput

0.571

High

556817

PSA1
Proteasome subunit alpha type-1

2

3

High-throughput

0.571

High

578187

ENO
Enolase

2

3

High-throughput

0.571

High

609512

PCNA
Proliferating cell nuclear antigen

2

3

High-throughput

0.571

High

649156

ANX10
Annexin B10

2

6

High-throughput

0.571

High

712456

CALR
Calreticulin

2

5

High-throughput

0.571

High

762675

UCHL
Ubiquitin carboxyl-terminal hydrolase

2

3

High-throughput

0.571

High

856183

MOEH
Moesin/ezrin/radixin homolog 1

2

4

High-throughput

0.571

High

929099

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

2

1

High-throughput

0.571

High

929618

PDI
Protein disulfide-isomerase

2

16

High-throughput

0.571

High

963897

SODC
Superoxide dismutase [Cu-Zn]

2

4

High-throughput

0.571

High

1019703

TRXR1
Thioredoxin reductase 1, mitochondrial

2

1

High-throughput

0.571

High

1176653

NLP
Nucleoplasmin-like protein

2

4

High-throughput

0.571

High

1306209

Q8IRD3
Glutathione peroxidase

2

1

High-throughput

0.571

High

1343095

Q8STA5
Histidine triad nucleotide binding protein 1, isoform A

2

2

High-throughput

0.571

High

1374640

NACA
Nascent polypeptide-associated complex subunit alpha

2

2

High-throughput

0.571

High

1445496

SH3BG
SH3 domain-binding glutamic acid-rich protein homolog

2

1

High-throughput

0.571

High

1483419

Q9VPN5
Stress-induced-phosphoprotein 1

2

7

High-throughput

0.571

High

1483715

Q9VPX6
Adenylyl cyclase-associated protein

2

1

High-throughput

0.571

High

1484853

Q9VRD6
NTF2-related export protein

2

2

High-throughput

0.571

High

1485696

Q9VSL2
Glutathione S transferase O3

2

2

High-throughput

0.571

High

1488592

CLIC
Chloride intracellular channel Clic

2

3

High-throughput

0.571

High

1489701

Q9XZ57
Eb1, isoform E

2

2

High-throughput

0.571

High

1427922

IF5A
Eukaryotic translation initiation factor 5A

2

0

High-throughput

0.547

High

1482192

ITPA
Inosine triphosphate pyrophosphatase

2

0

High-throughput

0.547

High

1487199

Y9705
Cold shock domain-containing protein CG9705

2

0

High-throughput

0.547

High

1489693

Q9W3Y3
Calcyclin-binding protein

2

0

High-throughput

0.547

High

838895

NCAH
Neurocalcin homolog

2

1

High-throughput

0.542

High

1478395

Q9VJD4
LD24721p

2

6

High-throughput

0.542

High

197905

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

2

2

High-throughput

0.521

High

356481

O97102
Small ubiquitin-related modifier

2

7

High-throughput

0.521

High

460217

ALF
Fructose-bisphosphate aldolase

2

1

High-throughput

0.521

High

477079

NDKA
Nucleoside diphosphate kinase

2

1

High-throughput

0.521

High

835239

6PGD
6-phosphogluconate dehydrogenase, decarboxylating

2

1

High-throughput

0.521

High

1262906

Q7JX87
1-Cys peroxiredoxin

2

7

High-throughput

0.521

High

1464646

Q9V3V9
Endonuclease G inhibitor, isoform A

2

1

High-throughput

0.521

High

1465096

THIO2
Thioredoxin-2

2

12

High-throughput

0.521

High

1476516

Q9VHN7
transketolase

2

1

High-throughput

0.521

High

1479953

Q9VKW5
Prolyl endopeptidase

2

3

High-throughput

0.521

High

1480391

Q9VL68
Enoyl-CoA delta isomerase 1, mitochondrial

2

1

High-throughput

0.521

High

1486353

Q9VTY2
Uncharacterized protein, isoform A

2

7

High-throughput

0.521

High

1486489

Q9VU35
10 kDa heat shock protein, mitochondrial

2

3

High-throughput

0.521

High

1487677

Q9VW59
Rho GDP-dissociation inhibitor 3

2

1

High-throughput

0.521

High

1489207

Q9W022
GEO01508p1

2

12

High-throughput

0.521

High

1489702

PSA6
Proteasome subunit alpha type-6

2

4

High-throughput

0.521

High

1485214

Q9VRV9
Importin N-terminal domain-containing protein

1

1

High-throughput

0.508

High

264574

MK38A
Mitogen-activated protein kinase p38a

1

5

Small-scale

0.479

High

1013279

MK14C
Putative mitogen-activated protein kinase 14C

1

5

Small-scale

0.479

High

1285722

Q86BM5
A kinase anchor protein 200, isoform D

1

6

High-throughput

0.479

High

1472407

Q9VEA1
Eukaryotic translation initiation factor 4C

1

1

High-throughput

0.479

High

1488791

Q9VYR1
Regucalcin

1

3

High-throughput

0.479

High

1267224

Q7KJA9
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.464

High

1488571

Q9VY48
Large ribosomal subunit protein mL38

1

3

High-throughput

0.464

High

1489611

Q9W1K1
GEO09102p1

1

1

High-throughput

0.464

High

53473

PKN
Serine/threonine-protein kinase N

1

3

High-throughput

0.445

High

57687

A1ZB71
Glutathione S transferase E6

1

1

High-throughput

0.445

High

121365

ALDR
Aldo-keto reductase 1B

1

7

High-throughput

0.445

High

234654

VINC
Vinculin

1

1

High-throughput

0.445

High

234809

O46067
Hypoxia up-regulated protein 1

1

6

High-throughput

0.445

High

262700

LOK
Ovarian-specific serine/threonine-protein kinase Lok

1

2

High-throughput

0.445

High

604375

CATA
Catalase

1

1

High-throughput

0.445

High

611563

PSA4
Proteasome subunit alpha type-4

1

3

High-throughput

0.445

High

633023

GLNA1
Glutamine synthetase 1, mitochondrial

1

1

High-throughput

0.445

High

648986

ANXB9
Annexin B9

1

6

High-throughput

0.445

High

682858

PROF
Profilin

1

1

High-throughput

0.445

High

757266

FAS2
Fasciclin-2

1

2

High-throughput

0.445

High

875507

KARG
Arginine kinase 1

1

1

High-throughput

0.445

High

968617

CALM
Calmodulin

1

5

High-throughput

0.445

High

1019964

1433E
14-3-3 protein epsilon

1

7

High-throughput

0.445

High

1061482

GRAP
Growth factor receptor-bound protein 2

1

6

High-throughput

0.445

High

1176838

NCPR
NADPH--cytochrome P450 reductase

1

2

High-throughput

0.445

High

1191745

Q3YMU0
Protein disulfide-isomerase

1

16

High-throughput

0.445

High

1260925

Q76NR6
Regucalcin

1

3

High-throughput

0.445

High

1265887

Q7K3J0
T-complex protein 1 subunit theta

1

1

High-throughput

0.445

High

1267291

Q7KKI0
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.445

High

1268013

TERA
Transitional endoplasmic reticulum ATPase TER94

1

2

High-throughput

0.445

High

1286153

QPCT2
Glutaminyl-peptide cyclotransferase

1

1

High-throughput

0.445

High

1305812

Q8IQZ7
FI19014p1

1

2

High-throughput

0.445

High

1322018

Q8MYY7
RE44624p

1

7

High-throughput

0.445

High

1343382

OLA1
Obg-like ATPase 1

1

3

High-throughput

0.445

High

1345336

Q8T0L3
E1 ubiquitin-activating enzyme

1

1

High-throughput

0.445

High

1440281

Q9I7K7
Arrestin C-terminal-like domain-containing protein

1

4

High-throughput

0.445

High

1464134

Q9V3Q4
thioredoxin-dependent peroxiredoxin

1

7

High-throughput

0.445

High

1465316

PDIA6
Protein disulfide-isomerase A6 homolog

1

12

High-throughput

0.445

High

1466539

AN32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A

1

8

High-throughput

0.445

High

1467787

Q9VAC4
GEO09167p1

1

4

High-throughput

0.445

High

1468704

Q9VAY2
Heat shock protein 83

1

10

High-throughput

0.445

High

1475994

TEBPH
Cytosolic Prostaglandin E synthase

1

3

High-throughput

0.445

High

1476324

Q9VHL2
T-complex protein 1 subunit eta

1

1

High-throughput

0.445

High

1478519

Q9VJJ0
Proteasome subunit beta

1

4

High-throughput

0.445

High

1479337

Q9VKB0
threonine--tRNA ligase

1

1

High-throughput

0.445

High

1480869

AK200
A-kinase anchor protein 200

1

8

High-throughput

0.445

High

1480924

SYAC
Alanine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

1481174

Q9VLS7
LD21067p

1

1

High-throughput

0.445

High

1484335

Q9VQL1
serine--tRNA ligase

1

1

High-throughput

0.445

High

1486635

Q9VUC1
Hsc70Cb, isoform A

1

7

High-throughput

0.445

High

1487709

Q9VW70
FI21813p1

1

2

High-throughput

0.445

High

1488842

TXND5
Thioredoxin domain-containing protein 5 homolog

1

17

High-throughput

0.445

High

1489346

Q9W0H8
Reticulocalbin-3

1

5

High-throughput

0.445

High

1489458

SND1
Staphylococcal nuclease domain-containing protein 1

1

1

High-throughput

0.445

High

1489698

Q9W4N8
LD30122p

1

2

High-throughput

0.445

High

1489700

Q9XYZ9
Glutathione S transferase E12, isoform A

1

2

High-throughput

0.445

High

120825

M9PE30
Transgelin

1

5

High-throughput

0.437

High

831792

CAB32
Calbindin-32

1

6

High-throughput

0.437

High

1303276

Q8IMG1
Uncharacterized protein, isoform C

1

5

High-throughput

0.437

High

1305157

Q8IQ53
GEO11416p1

1

2

High-throughput

0.437

High

1306713

Q8IRS7
Ciboulot, isoform C

1

2

High-throughput

0.437

High

1474876

Q9VGM2
Fatty acid-binding protein, muscle

1

3

High-throughput

0.437

High

57905

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.426

High

86616

B9EQV3
Endoplasmic reticulum transmembrane protein

1

0

High-throughput

0.426

High

146011

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.426

High

305760

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.426

High

356601

O97121
cystathionine gamma-lyase

1

0

High-throughput

0.426

High

1263188

SEELE
Protein seele

1

0

High-throughput

0.426

High

1264181

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

1268317

Q7KN99
Phosphopantothenoylcysteine synthetase, isoform A

1

0

High-throughput

0.426

High

1269533

Q7KTW5
Inositol-1-monophosphatase

1

0

High-throughput

0.426

High

1321765

Q8MT58
Carnosine dipeptidase 2, isoform A

1

0

High-throughput

0.426

High

1377747

FAXC
Failed axon connections

1

0

High-throughput

0.426

High

1440642

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.426

High

1445665

CP2B
Cardio acceleratory peptide 2b

1

0

High-throughput

0.426

High

1463356

Q9V3D8
GH27579p

1

0

High-throughput

0.426

High

1463733

Q9V3I1
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.426

High

1467930

Q9VAG3
trypsin

1

0

High-throughput

0.426

High

1475163

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.426

High

1476650

DPP3
Dipeptidyl peptidase 3

1

0

High-throughput

0.426

High

1486302

Q9VTX2
RE32936p

1

0

High-throughput

0.426

High

1489691

Q9W2M4
Farnesoic acid O-methyl transferase domain-containing protein

1

0

High-throughput

0.426

High

1489696

Q9W457
Serine hydroxymethyltransferase

1

0

High-throughput

0.426

High

1489697

Q9W478
RE43153p

1

0

High-throughput

0.426

High

1489703

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.426

High

47823

A0AQH0
Proteasome subunit beta

1

3

High-throughput

0.407

High

54123

A1Z892
1-Cys peroxiredoxin

1

7

High-throughput

0.407

High

357407

O97428
Ciboulot, isoform A

1

2

High-throughput

0.407

High

458154

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.407

High

627036

RLA0
Large ribosomal subunit protein uL10

1

3

High-throughput

0.407

High

652816

PSA71
Proteasome subunit alpha type-7-1

1

2

High-throughput

0.407

High

726525

VATB
V-type proton ATPase subunit B

1

6

High-throughput

0.407

High

821951

PSA2
Proteasome subunit alpha type-2

1

3

High-throughput

0.407

High

822115

PSB1
Proteasome subunit beta type-1

1

5

High-throughput

0.407

High

874743

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

1

High-throughput

0.407

High

1026686

SODM
Superoxide dismutase [Mn], mitochondrial

1

1

High-throughput

0.407

High

1031310

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.407

High

1052312

HMGD
High mobility group protein D

1

8

High-throughput

0.407

High

1052522

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.407

High

1176392

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

7

High-throughput

0.407

High

1176773

SAHH
Adenosylhomocysteinase

1

1

High-throughput

0.407

High

1262211

Q7JVH6
LD24696p

1

7

High-throughput

0.407

High

1263109

Q7JXC4
CG6459 protein

1

2

High-throughput

0.407

High

1264763

Q7K148
Proteasome subunit beta

1

3

High-throughput

0.407

High

1268131

Q7KN85
ATP-citrate synthase

1

1

High-throughput

0.407

High

1304010

Q8INK3
Fatty acid-binding protein, muscle

1

3

High-throughput

0.407

High

1344491

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.407

High

1374755

ACPM
Acyl carrier protein, mitochondrial

1

1

High-throughput

0.407

High

1374811

SUCA
Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

1376949

PSA5
Proteasome subunit alpha type-5

1

1

High-throughput

0.407

High

1378872

Q960D4
SD06560p

1

5

High-throughput

0.407

High

1440229

NASP
Nuclear autoantigenic sperm protein homolog

1

2

High-throughput

0.407

High

1466121

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.407

High

1467033

Q9V9U3
LD45254p

1

2

High-throughput

0.407

High

1468242

Q9VAN7
Phosphoglycerate mutase

1

3

High-throughput

0.407

High

1469044

Q9VB96
Uncharacterized protein, isoform A

1

1

High-throughput

0.407

High

1469557

Q9VBR6
RE74917p

1

2

High-throughput

0.407

High

1470447

ORN
Probable oligoribonuclease

1

1

High-throughput

0.407

High

1471023

Q9VD02
GH14779p

1

3

High-throughput

0.407

High

1471188

Q9VD29
small monomeric GTPase

1

3

High-throughput

0.407

High

1472985

FLNA
Filamin-A

1

7

High-throughput

0.407

High

1474385

Q9VG33
Sulfurtransferase

1

1

High-throughput

0.407

High

1476908

Q9VHX4
LD24679p

1

7

High-throughput

0.407

High

1477429

Q9VIE8
Aconitate hydratase, mitochondrial

1

2

High-throughput

0.407

High

1480106

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

2

High-throughput

0.407

High

1480210

EF1D
Probable elongation factor 1-delta

1

1

High-throughput

0.407

High

1480663

Q9VLB7
Rab GDP dissociation inhibitor

1

1

High-throughput

0.407

High

1482483

PSB4
Proteasome subunit beta type-4

1

8

High-throughput

0.407

High

1483096

Q9VP52
GH24315p

1

2

High-throughput

0.407

High

1483839

Q9VQ61
Aspartate aminotransferase

1

1

High-throughput

0.407

High

1484814

Q9VRD4
Uncharacterized protein, isoform A

1

1

High-throughput

0.407

High

1484980

Q9VRL1
GEO06356p1

1

2

High-throughput

0.407

High

1485056

Q9VRP2
Uncharacterized protein, isoform A

1

1

High-throughput

0.407

High

1486554

WDR1
Actin-interacting protein 1

1

7

High-throughput

0.407

High

1487369

Q9VVL7
Dihydrolipoyl dehydrogenase

1

1

High-throughput

0.407

High

1487994

Q9VWQ7
Coactosin-like protein

1

1

High-throughput

0.407

High

1488270

DHB4
Peroxisomal multifunctional enzyme type 2

1

1

High-throughput

0.407

High

1489053

Q9VZI1
Transgelin

1

6

High-throughput

0.407

High

1489185

Q9VZY0
LD45195p

1

2

High-throughput

0.407

High

1489692

Q9W3X6
fumarate hydratase

1

2

High-throughput

0.407

High

1489694

CISY
Probable citrate synthase, mitochondrial

1

2

High-throughput

0.407

High

1489695

WUHO
tRNA

1

5

High-throughput

0.407

High

1489699

PSB3
Proteasome subunit beta type-3

1

4

High-throughput

0.407

High

1489704

Q9Y112
BcDNA.GH10614

1

7

High-throughput

0.407

High

429116

RLA2
Large ribosomal subunit protein P2

2

0

High-throughput

0.310

High

1234398

Q6ILY6
GEO02508p1

2

0

High-throughput

0.310

High

52461

A1Z6X6
Lactoylglutathione lyase

2

0

High-throughput

0.298

High

1265347

Q7K2K2
FI04612p

2

0

High-throughput

0.298

High

1484161

BACC
Bacchus

2

0

High-throughput

0.298

High

234901

O46070
EG:25E8.4 protein

1

0

High-throughput

0.265

Low

1487539

Q9VW02
CG9283 protein

1

0

High-throughput

0.265

Low

53874

A1Z864
FI01421p

1

0

High-throughput

0.232

Low

304750

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.232

Low

305292

TRMB
tRNA

1

0

High-throughput

0.232

Low

426860

HP1
Heterochromatin protein 1

1

0

High-throughput

0.232

Low

614976

SYB
Synaptobrevin

1

0

High-throughput

0.232

Low

930264

VATE
V-type proton ATPase subunit E

1

0

High-throughput

0.232

Low

1014761

CYC2
Cytochrome c-2

1

0

High-throughput

0.232

Low

1070851

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.232

Low

1266835

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.232

Low

1440102

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.232

Low

1458053

GCSH
Glycine cleavage system H protein, mitochondrial

1

0

High-throughput

0.232

Low

1464555

SPC25
Kinetochore protein Spc25

1

0

High-throughput

0.232

Low

1467695

Q9VAC1
GM14349p

1

0

High-throughput

0.232

Low

1469642

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

1470561

Q9VCK6
LD34157p

1

0

High-throughput

0.232

Low

1474336

Q9VG31
Malic enzyme

1

0

High-throughput

0.232

Low

1477309

Q9VIC3
carboxylesterase

1

0

High-throughput

0.232

Low

1478132

RM13
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.232

Low

1480457

Q9VL70
HL08109p

1

0

High-throughput

0.232

Low

1481011

TCP4
RNA polymerase II transcriptional coactivator

1

0

High-throughput

0.232

Low

1482017

Q9VMU6
LD31822p

1

0

High-throughput

0.232

Low

1482264

GUAD
Guanine deaminase

1

0

High-throughput

0.232

Low

1482524

Q9VNB2
RE42193p

1

0

High-throughput

0.232

Low

1485443

Q9VS98
LD12639p

1

0

High-throughput

0.232

Low

1485646

Q9VSI6
Isocitrate dehydrogenase [NADP]

1

0

High-throughput

0.232

Low

1487849

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.232

Low

1488393

Q9VXQ3
Diphosphomevalonate decarboxylase

1

0

High-throughput

0.232

Low

1488672

Q9VYB9
LP02557p

1

0

High-throughput

0.232

Low

1489705

Q9Y170
Sex-regulated protein janus-B

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025