HitPredict

Interactor 1: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: MPP4 (Q9QYH1)
MAGUK p55 subfamily member 4 (Discs large homolog 6) (rDLG6)
Gene: MPP4

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10558890
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0032991 - protein-containing complex GO:0042734 - presynaptic membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 883 Rn			1 441
+	Hs
		786726 GRIA2_HUMAN (1-883): 0: 931: 99.55		DLG4_HUMAN (1-255): 4.66e-20: 95: 15.36
+	Mm
		620965 GRIA2_MOUSE (1-883): 0: 929: 99.89		DLG4_MOUSE (4-255): 4.97e-20: 95: 15.53
+	Hs
		786757 GRIA3_HUMAN (2-883): 0: 883: 71.80		DLG4_HUMAN (1-255): 4.66e-20: 95: 15.36
+	Mm
		1143566 GRIA3_MOUSE (2-883): 0: 881: 71.01		DLG4_MOUSE (4-255): 4.97e-20: 95: 15.53
+	Hs
		786696 GRIA1_HUMAN (4-868): 0: 870: 70.09		DLG1_HUMAN (4-85): 9.36e-20: 94.2: 19.32
+	Rn
		585138 GRIA1_RAT (4-868): 0: 867: 69.75		DLG4_RAT (1-255): 4.34e-20: 95: 15.36
+	Mm
		620904 GRIA1_MOUSE (4-868): 0: 863: 68.82		DLG2_MOUSE (4-265): 1.19e-21: 99: 11.26
+	Rn
		585151 GRIA1_RAT (4-868): 0: 867: 69.75		DLG1_RAT (4-91): 1.4e-19: 93.8: 18.09
+	Mm
		620892 GRIA1_MOUSE (4-868): 0: 863: 68.82		DLG4_MOUSE (4-255): 4.97e-20: 95: 15.53
+	Mm
		620881 GRIA1_MOUSE (4-868): 0: 863: 68.82		DLG3_MOUSE (4-89): 1.97e-16: 83.8: 20.65
+	Mm
		1143565 GRIA4_MOUSE (1-848): 0: 851: 73.19		DLG4_MOUSE (4-255): 4.97e-20: 95: 15.53
+	Hs
		942335 GRIK2_HUMAN (2-847): 0: 790: 38.75		DLG4_HUMAN (1-255): 4.66e-20: 95: 15.36
+	Hs
		1021483 GRIK2_HUMAN (2-847): 0: 790: 38.75		DLG1_HUMAN (4-85): 9.36e-20: 94.2: 19.32
+	Rn
		677766 GRIK2_RAT (3-847): 0: 788: 38.68		DLG4_RAT (1-255): 4.34e-20: 95: 15.36
+	Mm
		761217 GRIK2_MOUSE (3-847): 0: 788: 38.68		DLG4_MOUSE (4-255): 4.97e-20: 95: 15.53
+	Hs
		1022366 GRIK2_HUMAN (2-847): 0: 790: 38.75		DLG3_HUMAN (4-73): 1.7e-16: 84.2: 21.05
+	Hs
		761199 GRIK1_HUMAN (11-871): 0: 778: 37.03		DLG4_HUMAN (1-255): 4.66e-20: 95: 15.36
+	Hs
		942350 GRIK5_HUMAN (4-864): 0: 668: 33.98		DLG4_HUMAN (1-255): 4.66e-20: 95: 15.36
+	Mm
		1142982 GRIK5_MOUSE (4-864): 0: 666: 33.86		DLG4_MOUSE (4-255): 4.97e-20: 95: 15.53
+	Hs
		1081918 GRIK5_HUMAN (4-864): 0: 668: 33.98		DLG3_HUMAN (4-73): 1.7e-16: 84.2: 21.05