HitPredict

Interactor 1: CR2 (P20023)
Complement receptor type 2 (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD antigen CD21)
Gene: CR2

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	1383329
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001618 - virus receptor activity GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1033 Hs			1 236
+	Hs
		548833 MCP_HUMAN (789-1025): 2.39e-24: 108: 17.00		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		101394 F8VNQ3_HUMAN (4-295): 1.95e-20: 100: 12.18		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		548832 MCP_HUMAN (789-1025): 2.39e-24: 108: 17.00		CD151_HUMAN (3-231): 1.89e-54: 176: 25.40
+	Hs
		548826 MCP_HUMAN (789-1025): 2.39e-24: 108: 17.00		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		905569 TEN2_HUMAN (4-295): 6.48e-20: 98.6: 11.84		TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67
+	Hs
		548828 MCP_HUMAN (789-1025): 2.39e-24: 108: 17.00		CD82_HUMAN (4-234): 1.57e-49: 164: 23.11
+	Hs
		602286 TEN2_HUMAN (4-295): 6.48e-20: 98.6: 11.84		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		905571 TEN3_HUMAN (6-162): 1.12e-13: 78.2: 12.73		TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67
+	Hs
		602289 TEN3_HUMAN (6-162): 1.12e-13: 78.2: 12.73		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		326236 TEN2_HUMAN (4-295): 6.48e-20: 98.6: 11.84		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326243 TEN3_HUMAN (6-162): 1.12e-13: 78.2: 12.73		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48