Interactor 1: CD33 (P20138)
Myeloid cell surface antigen CD33 (Sialic acid-binding Ig-like lectin 3) (Siglec-3) (gp67) (CD antigen CD33)
Gene: CD33

Interactor 2: CD22 (P20273)
B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)
Gene: CD22

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 7537381
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~ig, Ig_2~ig, Ig_3~ig, C2-set_2~V-set, Ig_2~V-set, Ig_3~V-set
Common GO terms GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0009897 - external side of plasma membrane
GO:0009986 - cell surface
GO:0019903 - protein phosphatase binding
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 364
Hs

1 847
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dm
+ Dr
+ Dr
+ Hs
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024