HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TAF6 (P49848)
Transcription initiation factor TFIID subunit 6 (RNA polymerase II TBP-associated factor subunit E) (Transcription initiation factor TFIID 70 kDa subunit) (TAF(II)70) (TAFII-70) (TAFII70) (Transcription initiation factor TFIID 80 kDa subunit) (TAF(II)80) (TAFII-80) (TAFII80)
Gene: TAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.757

The method score is based on:

Property	Details
Experiments	12453419, 12665565, 9153318, 7680771, 35271311, 19240132, 17967894, 17375202, 8858156, 9603525, 22323595, 15870280, 9674425
Identification Methods	affinity chromatography technology, biochemical, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex GO:0006352 - DNA-templated transcription initiation GO:0006366 - transcription by RNA polymerase II and 7 others more... GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0017162 - aryl hydrocarbon receptor binding GO:0032991 - protein-containing complex GO:0042789 - mRNA transcription by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	339
Hs

1	677

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024