HitPredict

Interactor 1: TBP (P20227)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TAF4 (P47825)
Transcription initiation factor TFIID subunit 4 (110 kDa TBP-associated factor) (Transcription initiation factor TFIID 110 kDa subunit) (TAFII-110) (p110)
Gene: TAF4

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.964

The method score is based on:

Property Details
Experiments 11438676, 11493925, 7923382, 8178153, 8276241, 8327460, 16895980, 8464492
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains TAF4~TBP
Common GO terms GO:0001092 - TFIIA-class transcription factor complex binding
GO:0005634 - nucleus
GO:0005669 - transcription factor TFIID complex
GO:0006366 - transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter
and 2 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 353
Dm

1 921
+ Hs
+ Hs
+ Mm
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024