Interactor 1: CCNA2 (P20248)
Cyclin-A2 (Cyclin-A) (Cyclin A)
Gene: CCNA2

Interactor 2: CDN1A (P38936)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
Gene: CDKN1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 26186194, 28514442, 12947099, 33961781, 17679094, 9380407, 21308745, 8756624, 9660939, 26496610, 30833792, 8662825, 23443559, 8242751, 15890360
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation, anti tag coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Cyclin_N
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 432
Hs

1 164
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+ Mm
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+ Xl
+ Xl
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024