Interactor 1: CCNA2 (P20248)
Cyclin-A2 (Cyclin-A) (Cyclin A)
Gene: CCNA2
Interactor 2: CDN1A (P38936)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
Gene: CDKN1A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.96 | 1.00 | 0.983 |
The method score is based on:
Property | Details |
---|---|
Experiments | 26186194, 28514442, 12947099, 33961781, 17679094, 9380407, 21308745, 8756624, 9660939, 26496610, 30833792, 8662825, 23443559, 8242751, 15890360 |
Identification Methods | affinity chromatography technology, pull down, coimmunoprecipitation, anti tag coimmunoprecipitation, surface plasmon resonance |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | CDI~Cyclin_N |
Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 4 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024