HitPredict

Interactor 1: CCNA2 (P20248)
Cyclin-A2 (Cyclin-A) (Cyclin A)
Gene: CCNA2

Interactor 2: RBL2 (Q08999)
Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (p130) (Retinoblastoma-related protein 2) (RBR-2) (pRb2)
Gene: RBL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.732

Property	Details
Experiments	26186194, 28514442, 33961781, 8253383, 12006580, 17531812
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 1139
+	Hs
		943777 CCNA1_HUMAN (15-432): 7.29e-131: 386: 46.46		RBL2_HUMAN (1-1139): 0: 1591: 100.00
+	Hs
		538529 CCNB1_HUMAN (23-425): 1.93e-111: 336: 27.71		RBL2_HUMAN (1-1139): 0: 1591: 100.00
+	Hs
		590128 CCNA2_HUMAN (1-432): 1.56e-151: 438: 100.00		RBL1_HUMAN (51-1139): 0: 1396: 50.59
+	Hs
		660112 CCNA1_HUMAN (15-432): 7.29e-131: 386: 46.46		RBL1_HUMAN (51-1139): 0: 1396: 50.59
+	Hs
		414164 CCNA2_HUMAN (1-432): 1.56e-151: 438: 100.00		RB_HUMAN (775-999): 1.19e-64: 239: 29.39
+	Hs
		414240 CCNA1_HUMAN (15-432): 7.29e-131: 386: 46.46		RB_HUMAN (775-999): 1.19e-64: 239: 29.39
+	Hs
		414150 CCNB1_HUMAN (23-425): 1.93e-111: 336: 27.71		RB_HUMAN (775-999): 1.19e-64: 239: 29.39