HitPredict

Interactor 1: CEH63 (A3FPJ2)
Homeobox protein ceh-63
Gene: ceh-63

Interactor 2: HM14 (P20271)
LIM/homeobox protein ceh-14 (Homeobox protein ceh-14)
Gene: ceh-14

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22207033
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 152 Ce			1 351
+	Mm
		192277 ALX4_MOUSE (22-147): 1.03e-32: 120: 24.60		LMX1B_MOUSE (2-340): 2.84e-58: 195: 25.20
+	Hs
		1255789 LMX1A_HUMAN (5-152): 1.26e-30: 115: 16.67		LMX1A_HUMAN (43-347): 3.31e-59: 197: 26.05
+	Hs
		238103 HXA1_HUMAN (5-116): 1.58e-30: 113: 26.79		LMX1B_HUMAN (2-333): 3.05e-59: 197: 26.22
+	Hs
		899927 LMX1A_HUMAN (5-152): 1.26e-30: 115: 16.67		ISL1_HUMAN (42-336): 2.53e-51: 175: 21.28
+	Hs
		238115 LMX1B_HUMAN (1-152): 5.87e-31: 116: 15.12		ISL2_HUMAN (42-336): 1.11e-48: 169: 22.49
+	Dm
		447339 SCR_DROME (2-101): 7.55e-30: 113: 30.00		Q9VJ37_DROME (42-349): 2.46e-48: 172: 21.98
+	Hs
		446909 HXC4_HUMAN (14-123): 7.82e-33: 118: 30.91		LMO3_HUMAN (36-166): 8.22e-48: 160: 28.68
+	Hs
		238113 LMX1B_HUMAN (1-152): 5.87e-31: 116: 15.12		LMO3_HUMAN (36-166): 8.22e-48: 160: 28.68
+	Hs
		238099 LMX1B_HUMAN (1-152): 5.87e-31: 116: 15.12		RBTN1_HUMAN (25-165): 1.46e-43: 149: 28.77
+	Hs
		638486 MEOX2_HUMAN (2-112): 1.39e-31: 116: 31.53		RBTN1_HUMAN (25-165): 1.46e-43: 149: 28.77
+	Hs
		638515 Q6FHY5_HUMAN (2-112): 1.36e-31: 116: 31.53		RBTN1_HUMAN (25-165): 1.46e-43: 149: 28.77
+	Hs
		823411 ISX_HUMAN (27-148): 6.31e-30: 110: 26.23		PAXI_HUMAN (3-103): 2.47e-26: 111: 20.59
+	Hs
		238954 HXA1_HUMAN (5-116): 1.58e-30: 113: 26.79		LPXN_HUMAN (1-103): 7.52e-23: 99: 19.23
+	Hs
		1255791 LMX1A_HUMAN (5-152): 1.26e-30: 115: 16.67		LHX3_HUMAN (1-100): 1.1e-20: 94.2: 15.39
+	Dm
		447326 SCR_DROME (2-101): 7.55e-30: 113: 30.00		APTE_DROME (48-168): 1.67e-18: 88.2: 36.29
+	Hs
		238123 LMX1B_HUMAN (1-152): 5.87e-31: 116: 15.12		LHX6_HUMAN (4-100): 1.38e-16: 81.9: 19.80
+	Hs
		679132 TLX1_HUMAN (10-112): 2.59e-39: 136: 33.64		ZFHX4_HUMAN (181-250): 5.18e-09: 60.1: 28.57
+	Hs
		211902 TLX3_HUMAN (1-112): 5.44e-39: 135: 32.46		ZFHX4_HUMAN (181-250): 5.18e-09: 60.1: 28.57
+	Hs
		620171 PAX7_HUMAN (4-152): 1.93e-33: 124: 21.48		ZFHX4_HUMAN (181-250): 5.18e-09: 60.1: 28.57
+	Hs
		1101569 ISX_HUMAN (27-148): 6.31e-30: 110: 26.23		ZFHX4_HUMAN (181-250): 5.18e-09: 60.1: 28.57