Interactor 1: PO5F1 (P20263)
POU domain, class 5, transcription factor 1 (NF-A3) (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3)
Gene: Pou5f1

Interactor 2: CDX2 (P43241)
Homeobox protein CDX-2 (Caudal-type homeobox protein 2)
Gene: CDX2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 16325584
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain, Homeodomain~Pou
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001824 - blastocyst development
GO:0001829 - trophectodermal cell differentiation
GO:0003700 - DNA-binding transcription factor activity
and 9 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 352
Mm

1 311
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Ce
+ Hs
+ Mm
+ Ce
+ Mm
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Ce
+ Mm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024