HitPredict

Interactor 1: ACM3 (P20309)
Muscarinic acetylcholine receptor M3
Gene: CHRM3

Interactor 2: AT1A4 (Q13733)
Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4)
Gene: ATP1A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 590 Hs			1 1029
+	Hs
		530825 ACM3_HUMAN (1-590): 1.17e-140: 422: 100.00		AT1A3_HUMAN (35-1029): 0: 1001: 78.74
+	Hs
		436891 ACM4_HUMAN (42-564): 5.78e-83: 269: 40.80		AT1A3_HUMAN (35-1029): 0: 1001: 78.74
+	Hs
		392982 ADRB2_HUMAN (465-589): 6.79e-29: 121: 26.98		AT1A1_HUMAN (38-1029): 0: 1013: 79.68
+	Hs
		445768 ACM5_HUMAN (44-578): 9.59e-97: 307: 51.02		AT2A2_HUMAN (50-1020): 0: 771: 27.10
+	Hs
		530844 OPRX_HUMAN (447-577): 8.57e-14: 75.2: 15.67		AT1A3_HUMAN (35-1029): 0: 1001: 78.74
+	Hs
		530845 P2RY2_HUMAN (454-585): 4.13e-09: 60.5: 11.43		AT1A3_HUMAN (35-1029): 0: 1001: 78.74
+	Hs
		686624 CCR1_HUMAN (480-590): 1.8e-16: 82.9: 22.58		AT12A_HUMAN (4-1029): 0: 913: 61.03
+	Hs
		674839 AGTR1_HUMAN (451-584): 3.15e-14: 76.4: 15.39		AT12A_HUMAN (4-1029): 0: 913: 61.03
+	Hs
		781050 OPRX_HUMAN (447-577): 8.57e-14: 75.2: 15.67		AT12A_HUMAN (4-1029): 0: 913: 61.03
+	Hs
		782415 P2RY2_HUMAN (454-585): 4.13e-09: 60.5: 11.43		AT12A_HUMAN (4-1029): 0: 913: 61.03
+	Hs
		428908 ADRB2_HUMAN (465-589): 6.79e-29: 121: 26.98		AT2A2_HUMAN (50-1020): 0: 771: 27.10
+	Hs
		782452 P2RY2_HUMAN (454-585): 4.13e-09: 60.5: 11.43		AT2A3_HUMAN (51-1018): 0: 770: 27.83