HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RAB2A (P61019)
Ras-related protein Rab-2A (EC 3.6.5.2)
Gene: RAB2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0015031 - protein transport GO:0016192 - vesicle-mediated transport GO:0019003 - GDP binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 212
+	Hs
		895217 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB8B_HUMAN (2-199): 1.31e-94: 276: 45.46
+	Hs
		895204 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB2B_HUMAN (1-212): 1.08e-86: 256: 82.87
+	Mm
		867146 RAB2B_MOUSE (9-218): 1.48e-89: 264: 51.16		RAB2A_MOUSE (1-212): 2.61e-88: 260: 98.59
+	Hs
		895026 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1A_HUMAN (3-212): 3.93e-84: 249: 45.24
+	Hs
		895020 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB14_HUMAN (3-211): 2.23e-83: 248: 58.85
+	Hs
		895264 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		RAB1B_HUMAN (3-212): 7.6e-83: 246: 44.29
+	Hs
		591951 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB2B_HUMAN (1-212): 1.08e-86: 256: 82.87
+	Hs
		1273009 RAB8B_HUMAN (6-205): 1.17e-89: 264: 42.00		RAB1B_HUMAN (3-212): 7.6e-83: 246: 44.29
+	Hs
		591801 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB1A_HUMAN (3-212): 3.93e-84: 249: 45.24
+	Hs
		591795 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB14_HUMAN (3-211): 2.23e-83: 248: 58.85
+	Hs
		591800 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67
+	Zm
		73944 B4FAE1_MAIZE (6-217): 7.18e-86: 254: 39.15		B4FAE1_MAIZE (3-211): 1.08e-85: 253: 43.54
+	Mm
		880395 RAB4A_MOUSE (1-218): 5.01e-88: 260: 97.71		RAB1B_MOUSE (3-212): 1.1e-82: 245: 43.81
+	Hs
		896605 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RAB14_HUMAN (3-211): 2.23e-83: 248: 58.85
+	Hs
		913992 RAB1A_HUMAN (3-218): 3.01e-85: 252: 38.43		RB11A_HUMAN (3-212): 2.35e-83: 248: 46.67
+	Mm
		919000 RAB1A_MOUSE (3-218): 3.01e-85: 252: 38.43		RAB1B_MOUSE (3-212): 1.1e-82: 245: 43.81
+	Hs
		591793 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RAB4B_HUMAN (3-188): 4.24e-71: 217: 55.91