Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: DP13B (Q8NEU8)
DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2)
Gene: APPL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 29568061, 34079125, 15016378, 18034774
Identification Methods proximity labelling technology, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Ras
Common GO terms GO:0001726 - ruffle
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0010008 - endosome membrane
GO:0031901 - early endosome membrane
and 2 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 215
Hs

1 664
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024