HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: OSBL9 (Q96SU4)
Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9)
Gene: OSBPL9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 736
+	Hs
		844697 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSBL9_HUMAN (1-736): 0: 723: 100.00
+	Hs
		914300 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSBL9_HUMAN (1-736): 0: 723: 100.00
+	Hs
		592471 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSB10_HUMAN (3-730): 0: 545: 35.26
+	Hs
		592470 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSB11_HUMAN (7-729): 0: 540: 36.54
+	Hs
		844713 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSB11_HUMAN (7-729): 0: 540: 36.54
+	Hs
		914326 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSB10_HUMAN (3-730): 0: 545: 35.26
+	Hs
		914325 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSB11_HUMAN (7-729): 0: 540: 36.54
+	Hs
		592475 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		OSBL8_HUMAN (158-724): 1.29e-130: 410: 28.52
+	Dm
		90638 RAB5_DROME (6-213): 9.84e-98: 284: 75.00		E1JH23_DROME (270-677): 8.19e-127: 385: 52.81
+	Hs
		844716 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		OSBL8_HUMAN (158-724): 1.29e-130: 410: 28.52
+	Hs
		914333 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		OSBL8_HUMAN (158-724): 1.29e-130: 410: 28.52
+	Dm
		1358753 RAB5_DROME (6-213): 9.84e-98: 284: 75.00		Q9W0K9_DROME (7-114): 4.88e-16: 79.7: 37.50