HitPredict

Interactor 1: DBP4 (P20448)
ATP-dependent RNA helicase HCA4 (EC 3.6.4.13) (DEAD box protein 4) (Helicase CA4) (Helicase UF1)
Gene: HCA4

Interactor 2: DOA1 (P36037)
Protein DOA1 (Degradation of alpha protein 1) (Ubiquitin fusion degradation protein 3)
Gene: DOA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26349035
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 770 Sc			1 715
+	Sc
		593702 DBP4_YEAST (1-770): 3.32e-163: 492: 100.00		UTP13_YEAST (10-246): 5.07e-18: 90.9: 30.30
+	Hs
		1271700 DDX17_HUMAN (7-450): 2.25e-125: 393: 27.17		FBW1A_HUMAN (124-459): 4.96e-44: 169: 15.79
+	Hs
		1271615 DDX17_HUMAN (7-450): 2.25e-125: 393: 27.17		FBXW7_HUMAN (205-534): 1.17e-40: 160: 14.63
+	Hs
		571638 DDX5_HUMAN (7-468): 2.47e-122: 382: 26.94		FBW1A_HUMAN (124-459): 4.96e-44: 169: 15.79
+	Hs
		1288337 DDX18_HUMAN (2-537): 5.49e-149: 452: 35.61		SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29
+	Hs
		903549 DDX18_HUMAN (2-537): 5.49e-149: 452: 35.61		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Sc
		630886 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		NLE1_YEAST (177-534): 5.33e-37: 147: 14.40
+	Hs
		1271679 DDX17_HUMAN (7-450): 2.25e-125: 393: 27.17		NLE1_HUMAN (4-82): 1.98e-19: 93.9: 22.50
+	Hs
		1271621 DDX17_HUMAN (7-450): 2.25e-125: 393: 27.17		SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29
+	Hs
		903410 DDX17_HUMAN (7-450): 2.25e-125: 393: 27.17		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		571547 DDX5_HUMAN (7-468): 2.47e-122: 382: 26.94		SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29
+	Sc
		976856 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		UTP13_YEAST (10-246): 5.07e-18: 90.9: 30.30
+	Hs
		571382 DDX5_HUMAN (7-468): 2.47e-122: 382: 26.94		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		903381 DDX54_HUMAN (14-767): 4.85e-116: 373: 21.26		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Sc
		630853 DRS1_YEAST (43-418): 9.8e-52: 194: 32.38		NLE1_YEAST (177-534): 5.33e-37: 147: 14.40
+	Sc
		630846 SPB4_YEAST (55-489): 4.52e-52: 193: 31.36		NLE1_YEAST (177-534): 5.33e-37: 147: 14.40
+	Hs
		1333547 DDX31_HUMAN (64-488): 9.9e-58: 213: 32.60		NLE1_HUMAN (4-82): 1.98e-19: 93.9: 22.50
+	Hs
		903507 DDX47_HUMAN (39-405): 2.75e-61: 215: 35.87		WDR5_HUMAN (2-82): 7.4e-13: 72.3: 12.64
+	Hs
		1288310 DDX31_HUMAN (64-488): 9.9e-58: 213: 32.60		SNR40_HUMAN (4-83): 2.88e-13: 73.9: 15.29