Interactor 1: IF2A (P20459)
Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha) (eIF-2A) (eIF-2alpha) (eIF2-alpha)
Gene: SUI2

Interactor 2: IF2G (P32481)
Eukaryotic translation initiation factor 2 subunit gamma (eIF2-gamma) (EC 3.6.5.3)
Gene: GCD11

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.986

The method score is based on:

Property Details
Experiments 26211610, 11805837, 20485439, 23775072, 24852487, 18719252, 35031321, 16554755, 16429126, 24706853, 10769173, 16522633, 37968396, 18794367
Identification Methods two hybrid, anti tag coimmunoprecipitation, pull down, affinity chromatography technology, tandem affinity purification, mass spectrometry studies of complexes
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EIF_2_alpha~GTP_EFTU, EIF_2_alpha~GTP_EFTU_D2
Common GO terms GO:0001731 - formation of translation preinitiation complex
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0005840 - ribosome
GO:0005850 - eukaryotic translation initiation factor 2 complex
and 3 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 304
Sc

1 527
+ Hs
+ Dm
+ Hs
+ Sc
+ Hv
+ Ss
+ Dm
+ Ec

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Last updated: 15 Jul 2024