HitPredict

Interactor 1: SAR1 (P20606)
Small COPII coat GTPase SAR1 (EC 3.6.5.-) (GTP-binding protein SAR1) (Secretion-associated RAS-related protein 1)
Gene: SAR1

Interactor 2: SED5 (Q01590)
Integral membrane protein SED5
Gene: SED5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	12426382, 16107716
Identification Methods	affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005789 - endoplasmic reticulum membrane GO:0006886 - intracellular protein transport GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 190 Sc			1 340
+	At
		1152614 Q6ID97_ARATH (7-190): 6.38e-66: 201: 35.87		SYP32_ARATH (2-338): 2.86e-72: 229: 28.36
+	Hs
		1027600 SAR1B_HUMAN (6-190): 1.66e-76: 229: 59.79		STX5_HUMAN (1-324): 1.36e-52: 178: 29.01
+	Sc
		503127 ARF1_YEAST (7-190): 9.28e-65: 198: 34.24		SED5_YEAST (1-340): 6.94e-64: 207: 100.00
+	Hs
		1027573 SAR1A_HUMAN (6-190): 2.85e-75: 226: 59.79		STX5_HUMAN (1-324): 1.36e-52: 178: 29.01
+	Hs
		950607 ARF5_HUMAN (7-190): 7.65e-75: 224: 33.70		STX5_HUMAN (1-324): 1.36e-52: 178: 29.01
+	Hs
		574664 ARF4_HUMAN (7-190): 2.55e-74: 223: 34.24		STX5_HUMAN (1-324): 1.36e-52: 178: 29.01
+	Hs
		912882 ARF6_HUMAN (12-189): 1.83e-74: 223: 34.83		STX5_HUMAN (1-324): 1.36e-52: 178: 29.01
+	Sc
		594432 SAR1_YEAST (1-190): 4.51e-76: 227: 100.00		TLG2_YEAST (3-339): 8.21e-45: 159: 13.54
+	Hs
		912979 ARF6_HUMAN (12-189): 1.83e-74: 223: 34.83		STX12_HUMAN (78-328): 2.57e-47: 162: 17.06
+	Hs
		178806 SAR1A_HUMAN (6-190): 2.85e-75: 226: 59.79		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Hs
		178465 ARF6_HUMAN (12-189): 1.83e-74: 223: 34.83		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Hs
		914043 RB11A_HUMAN (13-190): 1.33e-62: 194: 16.39		STX5_HUMAN (1-324): 1.36e-52: 178: 29.01
+	Hs
		918901 RAB1A_HUMAN (13-190): 4.16e-66: 203: 19.13		STX12_HUMAN (78-328): 2.57e-47: 162: 17.06
+	Hs
		178468 RAB1A_HUMAN (13-190): 4.16e-66: 203: 19.13		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Sc
		503149 ARF1_YEAST (7-190): 9.28e-65: 198: 34.24		TLG2_YEAST (3-339): 8.21e-45: 159: 13.54
+	Hs
		1079938 RB11B_HUMAN (13-190): 1.47e-62: 194: 16.39		STX12_HUMAN (78-328): 2.57e-47: 162: 17.06
+	Hs
		178480 ARF1_HUMAN (7-190): 5.16e-64: 196: 34.24		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Hs
		178466 RB11A_HUMAN (13-190): 1.33e-62: 194: 16.39		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Hs
		178552 RB11B_HUMAN (13-190): 1.47e-62: 194: 16.39		STX7_HUMAN (95-320): 2.58e-45: 157: 18.50
+	Hs
		914044 RB11A_HUMAN (13-190): 1.33e-62: 194: 16.39		STX3_HUMAN (90-321): 5.45e-44: 154: 12.39