HitPredict

Interactor 1: NUP1 (P20676)
Nucleoporin NUP1 (Nuclear pore protein NUP1)
Gene: NUP1

Interactor 2: MTR10 (Q99189)
mRNA transport regulator MTR10
Gene: MTR10

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	9412460, 9368759
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1076 Sc			1 972
+	Sc
		595000 NUP1_YEAST (1-1076): 2e-160: 505: 100.00		XPO1_YEAST (2-969): 6.84e-139: 445: 13.57
+	Hs
		162517 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Hs
		162707 TCOF_HUMAN (12-1073): 2.61e-75: 274: 9.86		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Sc
		774386 NU159_YEAST (347-936): 2.15e-17: 90.3: 14.33		MTR10_YEAST (1-972): 0: 633: 100.00
+	Hs
		834652 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		TNPO1_HUMAN (68-873): 5.04e-133: 424: 12.89
+	Sc
		830686 NU145_YEAST (600-948): 1.92e-11: 70.7: 12.22		MTR10_YEAST (1-972): 0: 633: 100.00
+	Hs
		127218 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		IPO5_HUMAN (66-949): 1.35e-124: 407: 13.58
+	Hs
		155550 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		TNPO2_HUMAN (42-865): 1.06e-123: 399: 12.62
+	Hs
		834671 NU153_HUMAN (3-977): 5.82e-79: 285: 14.89		XPO5_HUMAN (1-825): 5.84e-108: 364: 11.76
+	Hs
		162534 NUP98_HUMAN (204-882): 2.45e-12: 73.8: 14.55		XPO1_HUMAN (2-959): 3.01e-161: 503: 12.60
+	Dm
		1353152 Q9VLS7_DROME (126-1063): 5.48e-19: 95.6: 8.93		XPO1_DROME (2-963): 6.19e-150: 473: 12.41
+	Sc
		676117 NU159_YEAST (347-936): 2.15e-17: 90.3: 14.33		XPO1_YEAST (2-969): 6.84e-139: 445: 13.57
+	Sc
		541850 NSP1_YEAST (511-1032): 4.79e-13: 75.7: 16.10		XPO1_YEAST (2-969): 6.84e-139: 445: 13.57
+	Sc
		676198 NU145_YEAST (600-948): 1.92e-11: 70.7: 12.22		XPO1_YEAST (2-969): 6.84e-139: 445: 13.57
+	Hs
		858024 NUP98_HUMAN (204-882): 2.45e-12: 73.8: 14.55		TNPO1_HUMAN (68-873): 5.04e-133: 424: 12.89
+	Xl
		1137359 NU153_XENLA (347-1043): 2.87e-11: 70.3: 15.26		Q5U4V0_XENLA (70-873): 4.54e-131: 419: 13.26
+	Hs
		127345 P121A_HUMAN (51-1071): 1.05e-14: 81.4: 11.47		IPO5_HUMAN (66-949): 1.35e-124: 407: 13.58
+	Hs
		155553 NUP98_HUMAN (204-882): 2.45e-12: 73.8: 14.55		TNPO2_HUMAN (42-865): 1.06e-123: 399: 12.62
+	Sc
		691618 NUP2_YEAST (435-840): 1.31e-31: 135: 25.17		XPOT_YEAST (6-770): 2.07e-26: 119: 11.76
+	Sc
		541864 NSP1_YEAST (511-1032): 4.79e-13: 75.7: 16.10		XPOT_YEAST (6-770): 2.07e-26: 119: 11.76