Protein: UBP15
Ubiquitin carboxyl-terminal hydrolase 15 (EC 3.4.19.12) (Deubiquitinating enzyme 15) (Ubiquitin thioesterase 15) (Ubiquitin-specific-processing protease 15)

Gene: UBP15, Usp15
Organism: Mus musculus
Interactions: 98
UniProt ID: Q8R5H1

Gene Ontology (top 5):
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005160 - transforming growth factor beta receptor binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

509195

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

2

20

Small-scale

0.768

High

969113

PRS8
26S proteasome regulatory subunit 8

1

7

Small-scale

0.618

High

1230530

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

17

High-throughput

0.618

High

1282293

FACD2
Fanconi anemia group D2 protein homolog

1

1

High-throughput

0.618

High

1298103

WDR26
WD repeat-containing protein 26

1

4

High-throughput

0.618

High

1341662

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

17

High-throughput

0.618

High

1274433

MYCB2
E3 ubiquitin-protein ligase MYCBP2

2

7

Small-scale

0.584

High

1341690

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

2

5

Small-scale

0.584

High

932169

PRS6B
26S proteasome regulatory subunit 6B

1

5

Small-scale

0.553

High

1341676

CADM3
Cell adhesion molecule 3

1

1

High-throughput

0.553

High

1341687

STRN3
Striatin-3

1

7

High-throughput

0.553

High

1295911

PSD11
26S proteasome non-ATPase regulatory subunit 11

2

4

Small-scale

0.533

High

1341671

PSMD6
26S proteasome non-ATPase regulatory subunit 6

2

5

Small-scale

0.533

High

1341682

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

5

Small-scale

0.533

High

1341698

PSD13
26S proteasome non-ATPase regulatory subunit 13

2

3

Small-scale

0.533

High

204949

RABE1
Rab GTPase-binding effector protein 1

1

16

High-throughput

0.479

High

204972

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

8

High-throughput

0.479

High

237107

SYUA
Alpha-synuclein

1

4

High-throughput

0.479

High

313320

MKLN1
Muskelin

1

5

High-throughput

0.479

High

534025

H10
Histone H1.0

1

1

High-throughput

0.479

High

558931

RL7A
Large ribosomal subunit protein eL8

1

3

High-throughput

0.479

High

574841

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

Small-scale

0.479

High

602936

ENOA
Alpha-enolase

1

3

High-throughput

0.479

High

607847

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

8

High-throughput

0.479

High

776016

PRDX1
Peroxiredoxin-1

1

4

High-throughput

0.479

High

871193

DCE1
Glutamate decarboxylase 1

1

1

High-throughput

0.479

High

948048

DOCK4
Dedicator of cytokinesis protein 4

1

4

High-throughput

0.479

High

974351

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

7

Small-scale

0.479

High

974894

LSM5
U6 snRNA-associated Sm-like protein LSm5

1

4

Small-scale

0.479

High

980663

H4
Histone H4

1

4

High-throughput

0.479

High

999470

RANB9
Ran-binding protein 9

1

9

High-throughput

0.479

High

1009927

TCPH
T-complex protein 1 subunit eta

1

7

High-throughput

0.479

High

1017522

ISC2A
Isochorismatase domain-containing protein 2A

1

1

High-throughput

0.479

High

1188712

STING
Stimulator of interferon genes protein

1

5

High-throughput

0.479

High

1191009

LRRF1
Leucine-rich repeat flightless-interacting protein 1

1

1

High-throughput

0.479

High

1210036

GRDN
Girdin

1

19

High-throughput

0.479

High

1222123

XIAP
E3 ubiquitin-protein ligase XIAP

1

14

Small-scale

0.479

High

1223382

MYH10
Myosin-10

1

10

High-throughput

0.479

High

1243542

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

1257320

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

5

Small-scale

0.479

High

1274670

MRCKB
Serine/threonine-protein kinase MRCK beta

1

3

High-throughput

0.479

High

1281895

MON2
Protein MON2 homolog

1

1

High-throughput

0.479

High

1283040

MYOME
Myomegalin

1

12

High-throughput

0.479

High

1341545

CDC16
Cell division cycle protein 16 homolog

1

7

High-throughput

0.479

High

1341559

STPAP
Speckle targeted PIP5K1A-regulated poly(A) polymerase

1

2

Small-scale

0.479

High

1341663

MYH9
Myosin-9

1

10

High-throughput

0.479

High

1341665

SMAP1
Stromal membrane-associated protein 1

1

1

High-throughput

0.479

High

1341669

SYUB
Beta-synuclein

1

4

High-throughput

0.479

High

1341670

BICD2
Protein bicaudal D homolog 2

1

15

High-throughput

0.479

High

1341672

PARK7
Parkinson disease protein 7 homolog

1

1

High-throughput

0.479

High

1341673

RB6I2
ELKS/Rab6-interacting/CAST family member 1

1

14

High-throughput

0.479

High

1341674

ARBK1
Beta-adrenergic receptor kinase 1

1

5

High-throughput

0.479

High

1341675

Q99N15
3-hydroxyacyl-CoA dehydrogenase type-2

1

1

High-throughput

0.479

High

1341679

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

6

Small-scale

0.479

High

1341681

ATAD1
Outer mitochondrial transmembrane helix translocase

1

11

High-throughput

0.479

High

1341689

FLII
Protein flightless-1 homolog

1

3

High-throughput

0.479

High

1341691

RABX5
Rab5 GDP/GTP exchange factor

1

4

High-throughput

0.479

High

1341693

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

4

Small-scale

0.479

High

1341694

COPG1
Coatomer subunit gamma-1

1

3

High-throughput

0.479

High

1341695

PSA1
Proteasome subunit alpha type-1

1

3

Small-scale

0.479

High

1341697

SKP1
S-phase kinase-associated protein 1

1

3

High-throughput

0.479

High

1341699

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

4

High-throughput

0.479

High

1341683

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

7

Small-scale

0.470

High

926889

STMN1
Stathmin

1

0

High-throughput

0.458

High

940546

ACYP2
Acylphosphatase-2

1

0

High-throughput

0.458

High

1190955

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

0

High-throughput

0.458

High

1210681

SYNRG
Synergin gamma

1

0

High-throughput

0.458

High

1244311

WASC2
WASH complex subunit 2

1

0

High-throughput

0.458

High

1282970

RBNS5
Rabenosyn-5

1

0

High-throughput

0.458

High

1295980

BOLA2
BolA-like protein 2

1

0

High-throughput

0.458

High

1341666

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.458

High

1341667

Q91YS4
Kinesin light chain

1

0

High-throughput

0.458

High

1341680

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1341688

LZTL1
Leucine zipper transcription factor-like protein 1

1

0

High-throughput

0.458

High

1341686

XPO7
Exportin-7

1

9

High-throughput

0.445

High

59306

MA7D2
MAP7 domain-containing protein 2

1

13

High-throughput

0.437

High

312115

S4A4
Electrogenic sodium bicarbonate cotransporter 1

1

1

High-throughput

0.437

High

687003

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

8

High-throughput

0.437

High

844311

TCPQ
T-complex protein 1 subunit theta

1

9

High-throughput

0.437

High

1009976

TCPE
T-complex protein 1 subunit epsilon

1

7

High-throughput

0.437

High

1021290

VPS45
Vacuolar protein sorting-associated protein 45

1

2

High-throughput

0.437

High

1189376

ML12B
Myosin regulatory light chain 12B

1

3

High-throughput

0.437

High

1221209

MYL6
Myosin light polypeptide 6

1

4

High-throughput

0.437

High

1240009

MTCL3
Microtubule cross-linking factor 3

1

10

High-throughput

0.437

High

1297993

SEP11
Septin-11

1

2

High-throughput

0.437

High

1298573

AGRB2
Adhesion G protein-coupled receptor B2

1

1

High-throughput

0.437

High

1341664

ISOC1
Isochorismatase domain-containing protein 1

1

1

High-throughput

0.437

High

1341668

DIRA1
GTP-binding protein Di-Ras1

1

6

High-throughput

0.437

High

1341677

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

2

High-throughput

0.437

High

1341678

RRBP1
Ribosome-binding protein 1

1

12

High-throughput

0.437

High

1341684

DJC10
DnaJ homolog subfamily C member 10

1

3

Small-scale

0.437

High

1341692

MY18A
Unconventional myosin-XVIIIa

1

12

High-throughput

0.437

High

1341696

SEPT6
Septin-6

1

2

High-throughput

0.437

High

1341700

SE1L1
Protein sel-1 homolog 1

1

4

Small-scale

0.437

High

46584

SIM43
Small integral membrane protein 43

1

0

High-throughput

0.249

Low

1043837

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

0

High-throughput

0.249

Low

1341685

IPP2
Protein phosphatase inhibitor 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025