HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29844126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 2517
+	Hs
		360312 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		975718 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		1205250 K2C73_HUMAN (2-391): 1.07e-53: 193: 19.70		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		443743 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		CIC_HUMAN (1-2517): 0: 961: 100.00
+	Hs
		531540 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		595134 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Mm
		539724 LMNB1_MOUSE (5-586): 2.21e-69: 236: 95.54		SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44
+	Hs
		817952 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		SOX2_HUMAN (1073-1308): 2.83e-57: 204: 24.05
+	Hs
		360221 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		BBX_HUMAN (1078-1189): 1.69e-34: 147: 48.21
+	Hs
		975642 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		SOX4_HUMAN (1091-1186): 2.77e-25: 114: 31.25
+	Hs
		359942 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		MDC1_HUMAN (1380-2408): 4.76e-21: 104: 10.30
+	Mm
		589617 VIME_MOUSE (28-390): 1.46e-29: 123: 28.38		SOX2_MOUSE (1102-1308): 3.32e-55: 198: 26.44
+	Hs
		595471 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		360546 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		360224 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		TITIN_HUMAN (609-1544): 3.51e-09: 65.2: 9.85
+	Hs
		443800 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		TARA_HUMAN (523-2026): 3.76e-17: 91.1: 11.33
+	Hs
		443883 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		SRRM2_HUMAN (291-1369): 4.76e-10: 67.9: 8.34
+	Hs
		443464 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78
+	Hs
		781878 PERI_HUMAN (28-390): 1.66e-25: 111: 30.79		ANK2_HUMAN (535-2225): 4.48e-09: 64.6: 9.78