HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: NUP50 (Q9UKX7)
Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50)
Gene: NUP50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005654 - nucleoplasm GO:0031965 - nuclear membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 468
+	Hs
		360532 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Dr
		71514 B3DKC5_DANRE (6-573): 3.64e-58: 207: 50.76		Q6P0F8_DANRE (1-466): 1.91e-91: 285: 50.00
+	Hs
		595127 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Hs
		595145 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RBP2_HUMAN (212-468): 1.6e-36: 146: 17.60
+	Hs
		360329 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		RGPD5_HUMAN (196-468): 4.34e-39: 153: 14.34
+	Hs
		359736 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Hs
		359763 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		RBP2_HUMAN (212-468): 1.6e-36: 146: 17.60