HitPredict

Interactor 1: BCL3 (P20749)
B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3)
Gene: BCL3

Interactor 2: NFKB2 (Q00653)
Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]
Gene: NFKB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 8453667, 28689659, 30833792, 20558726, 20800578, 12808109, 16108830
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Ank_2, Ank~RHD_dimer, Ank_2~Ank_2, Ank_2~RHD_dimer
Common GO terms GO:0002268 - follicular dendritic cell differentiation
GO:0002467 - germinal center formation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 454
Hs

1 900
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Last updated: 15 Jul 2024