HitPredict

Interactor 1: BCL3 (P20749)
B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3)
Gene: BCL3

Interactor 2: BARD1 (Q99728)
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: BARD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.680

Property	Details
Experiments	10362352
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0006974 - DNA damage response GO:0043066 - negative regulation of apoptotic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 777
+	Hs
		1349604 RAI14_HUMAN (120-426): 2.96e-81: 271: 27.76		ANR50_HUMAN (287-668): 9.4e-63: 231: 14.55
+	Hs
		862012 DAPK1_HUMAN (165-452): 5.01e-59: 211: 18.97		DAPK1_HUMAN (194-574): 1.25e-79: 281: 15.62
+	Hs
		166882 BCL3_HUMAN (1-454): 1.07e-97: 302: 100.00		ANR28_HUMAN (221-515): 1.02e-47: 185: 17.16
+	Hs
		862028 DAPK1_HUMAN (165-452): 5.01e-59: 211: 18.97		ANK2_HUMAN (104-622): 2.47e-71: 257: 14.31
+	Mm
		103608 ANK2_MOUSE (211-454): 1.89e-47: 177: 20.31		ANK3_MOUSE (104-622): 8.12e-77: 273: 14.69
+	Hs
		166969 ANR44_HUMAN (43-453): 5.31e-76: 258: 15.76		ANR28_HUMAN (221-515): 1.02e-47: 185: 17.16
+	Hs
		883496 RIPK4_HUMAN (176-453): 2.16e-48: 179: 19.36		ANK3_HUMAN (268-703): 3.36e-72: 260: 14.86
+	Hs
		1021462 Q9H4D1_HUMAN (176-453): 5.85e-48: 177: 19.71		ANK3_HUMAN (268-703): 3.36e-72: 260: 14.86
+	Hs
		1304468 EHMT1_HUMAN (176-446): 2.67e-51: 188: 18.98		MPP8_HUMAN (119-549): 1.23e-51: 195: 15.51
+	Hs
		166913 ANK2_HUMAN (211-454): 7.66e-48: 179: 20.31		ANR28_HUMAN (221-515): 1.02e-47: 185: 17.16
+	Mm
		1322330 RIPK4_MOUSE (127-274): 5.03e-37: 146: 27.27		RIPK4_MOUSE (245-634): 4.7e-32: 135: 18.22
+	Hs
		965154 ANK2_HUMAN (211-454): 7.66e-48: 179: 20.31		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		883460 RIPK4_HUMAN (176-453): 2.16e-48: 179: 19.36		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59
+	Hs
		883487 ANK2_HUMAN (211-454): 7.66e-48: 179: 20.31		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59
+	Hs
		1330845 Q9H4D1_HUMAN (176-453): 5.85e-48: 177: 19.71		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		1330891 ANKR6_HUMAN (119-298): 6.73e-39: 151: 28.33		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		883678 ANKR6_HUMAN (119-298): 6.73e-39: 151: 28.33		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59