Interactor 1: CD3Z (P20963)
T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247)
Gene: CD247
Interactor 2: ZAP70 (P43403)
Tyrosine-protein kinase ZAP-70 (EC 2.7.10.2) (70 kDa zeta-chain associated protein) (Syk-related tyrosine kinase)
Gene: ZAP70
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.761 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30863395, 9036949, 20637659, 26390156, 22242145, 8647168, 7737297, 11353765, 8906806, 24463463, 7522230, 10752619, 15832366, 7528772, 9185620, 8901551, 8648092, 21957439, 10704231, 7509083 |
| Identification Methods | affinity chromatography technology, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, isothermal titration calorimetry, peptide array, pull down, surface plasmon resonance, enzymatic study, anti bait coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002250 - adaptive immune response GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0042101 - T cell receptor complex GO:0050852 - T cell receptor signaling pathway |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
