HitPredict

Interactor 1: CD11B (P21127)
Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)
Gene: CDK11B

Interactor 2: CDC37 (Q16543)
Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed]
Gene: CDC37

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

Property	Details
Experiments	24189400, 33961781, 35271311, 15344906
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CDC37_M~Pkinase, CDC37_N~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 795 Hs			1 378
+	Hs
		1083048 CD11A_HUMAN (1-795): 0: 561: 96.86		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		625464 CDK2_HUMAN (435-731): 1.45e-154: 454: 43.96		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		414935 CDK1_HUMAN (435-726): 7.24e-138: 411: 41.84		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		960287 CDK5_HUMAN (435-729): 1.29e-137: 410: 41.55		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		1068437 CDK10_HUMAN (429-760): 3.17e-133: 401: 52.41		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Hs
		841214 CDK7_HUMAN (436-760): 1.13e-72: 243: 38.69		CDC37_HUMAN (1-378): 2.03e-169: 479: 100.00
+	Sc
		339332 CDK1_YEAST (438-726): 1.02e-78: 257: 47.28		CDC37_YEAST (2-320): 1.81e-73: 238: 18.34